Frezzini Cristina, Cedro Monika, Leao Jair C, Porter Stephen
Division of Maxillofacial Diagnostic, Medical and Surgical Sciences, Eastman Dental Institute for Oral Health Care Sciences, University College London, London, UK.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Oct;102(4):e29-33. doi: 10.1016/j.tripleo.2005.10.040. Epub 2006 Aug 10.
Darier disease is an uncommon genodermatosis reflecting defective desmosomal structure and function. The present report details the oral features of a patient with well-characterized Darier disease and reviews current knowledge of the genetic basis of this genodermatosis that can often affect the craniofacial tissues.
毛囊角化病是一种罕见的遗传性皮肤病,反映了桥粒结构和功能的缺陷。本报告详细描述了一名具有典型毛囊角化病患者的口腔特征,并综述了这种常影响颅面部组织的遗传性皮肤病的遗传基础的现有知识。