Forman D, Burley V J
Cancer Epidemiology Group, Centre for Epidemiology and Biostatistics, University of Leeds, Leeds, UK.
Best Pract Res Clin Gastroenterol. 2006;20(4):633-49. doi: 10.1016/j.bpg.2006.04.008.
This first part of this chapter looks at the worldwide burden of gastric cancer at the beginning of the 21st century and summarises available population-based routine data that describes the variation in incidence of the disease in relation to age, sex, geography and time period. Consideration is also given to the differences in the descriptive epidemiology of gastric cancer arising in the proximal cardia region of the stomach. In the second part of the chapter, a brief review of the main identified environmental risk factors is conducted drawing, where available, on published systematic literature overviews and meta-analyses. Evidence relating the aetiology of gastric cancer to Helicobacter pylori infection, dietary factors, smoking, occupation, physical activity and anthropometry is presented.
本章的第一部分探讨了21世纪初全球胃癌负担，并总结了现有的基于人群的常规数据，这些数据描述了该疾病发病率在年龄、性别、地理区域和时间段方面的差异。同时还考虑了胃癌在胃近端贲门区域的描述性流行病学差异。在本章的第二部分，对已确定的主要环境风险因素进行了简要回顾，如有可能，参考了已发表的系统文献综述和荟萃分析。文中呈现了胃癌病因与幽门螺杆菌感染、饮食因素、吸烟、职业、身体活动和人体测量学之间的证据。
