Zemon Vance, Gordon James
Ferkauf Graduate School of Psychology, Yeshiva University, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.
Vision Res. 2006 Nov;46(24):4163-80. doi: 10.1016/j.visres.2006.07.007. Epub 2006 Sep 25.
Isolated-checks were luminance-modulated temporally to elicit VEPs. Bright or dark checks were used to drive ON or OFF pathways, and low or high-contrast conditions were used to emphasize activity from magnocellular or parvocellular pathways. Manipulation of stimulus parameters and frequency analysis of the VEP were performed to obtain spatial and contrast-response functions. A biophysical explanation is offered for why the opposite polarity stimuli drive selectively ON and OFF pathways in primary visual cortex, and a lumped biophysical model is proposed to quantify the data and characterize changes in the dynamics of the system with contrast given a limited number of parameters. Response functions were found to match the characteristics of the targeted pathways.
对孤立的方格进行时间上的亮度调制以引出视觉诱发电位（VEP）。使用亮方格或暗方格来驱动开通路或关通路，并且使用低对比度或高对比度条件来强调大细胞通路或小细胞通路的活动。通过操纵刺激参数和对VEP进行频率分析来获得空间和对比度响应函数。对于相反极性刺激为何在初级视觉皮层中选择性地驱动开通路和关通路给出了生物物理学解释，并提出了一个集总生物物理模型，以便在给定有限数量参数的情况下量化数据并表征系统动力学随对比度的变化。发现响应函数与目标通路的特征相匹配。
