Seress L, Ribak C E
Department of Anatomy and Neurobiology, University of California, Irvine 92717.
Exp Brain Res. 1990;81(3):500-8. doi: 10.1007/BF02423498.
Recent studies have indicated that hippocampal basket cells in both the dentate gyrus and Ammon's horn develop their somal and dendritic features during the first two postnatal weeks in rats. Their axon terminals form exclusively symmetric synapses that are found as early as 5 postnatal days in both regions. The present study used Golgi-electron microscopic material from 10 and 16 day old rats to demonstrate that the axon terminals of basket cells form synapses not only with somata, dendrites, and dendritic spines as reported for adult material but also with axon initial segments. However, the terminals forming synapses with axon initial segments and dendritic spines represent only a minor portion of the total number of basket cell terminals. Quantitative results indicate that 36-62% of the total number of these terminals form axosomatic synapses and 32-50% form axodendritic synapses depending on the analyzed cell. These data indicate that hippocampal basket cells have an axonal distribution similar to that found for cortical basket cells.
最近的研究表明，大鼠出生后的前两周内，齿状回和海马角的海马篮状细胞发育出其胞体和树突特征。它们的轴突终末仅形成对称突触，早在出生后5天就在这两个区域发现了这种突触。本研究使用来自10日龄和16日龄大鼠的高尔基电子显微镜材料，以证明篮状细胞的轴突终末不仅如成年材料报道的那样与胞体、树突和树突棘形成突触，还与轴突起始段形成突触。然而，与轴突起始段和树突棘形成突触的终末仅占篮状细胞终末总数的一小部分。定量结果表明，这些终末总数的36%-62%形成轴-体突触，32%-50%形成轴-树突触，这取决于所分析的细胞。这些数据表明，海马篮状细胞的轴突分布与皮质篮状细胞的相似。
