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连合纤维终止于豚鼠海马体的非锥体神经元——一项高尔基染色法/电子显微镜变性研究。

Commissural fibers terminate on non-pyramidal neurons in the guinea pig hippocampus -- a combined Golgi/EM degeneration study.

作者信息

Frotscher M, Zimmer J

出版信息

Brain Res. 1983 Apr 18;265(2):289-93. doi: 10.1016/0006-8993(83)90344-x.

DOI:10.1016/0006-8993(83)90344-x
PMID:6850332
Abstract

The combined Golgi/EM method was applied to guinea pig hippocampi with acute anterograde degeneration of the commissural afferents in order to identify possible synaptic contacts between commissural terminals and non-pyramidal neurons. Degenerating, electron-dense terminals of commissural origin were found in synaptic contact with both perikarya and dendrites of two identified non-pyramidal neurons in regio superior, namely a basket cell and a bipolar neuron in stratum oriens. The observed connection may form the morphological basis for the physiologically observed feed-forward inhibition of the pyramidal cells.

摘要

采用高尔基染色法与电子显微镜技术相结合的方法,对豚鼠海马体进行研究,该海马体的连合传入纤维存在急性顺行性变性,目的是确定连合终末与非锥体神经元之间可能存在的突触联系。在海马体上部区域,发现源自连合的变性、电子致密终末与两种已确定的非锥体神经元的胞体和树突形成突触联系,这两种神经元分别是篮状细胞和海马下托层的双极神经元。观察到的这种连接可能为生理学上观察到的锥体细胞前馈抑制形成形态学基础。

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