BOX元件调节肺炎链球菌中的基因表达：对感受态发育微调的影响。
BOX elements modulate gene expression in Streptococcus pneumoniae: impact on the fine-tuning of competence development.
作者信息
Knutsen Eivind, Johnsborg Ola, Quentin Yves, Claverys Jean-Pierre, Håvarstein Leiv Sigve
机构信息
Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, As, Norway.
出版信息
J Bacteriol. 2006 Dec;188(23):8307-12. doi: 10.1128/JB.00850-06. Epub 2006 Sep 22.
Abstract
More than 100 BOX elements are randomly distributed in intergenic regions of the pneumococcal genome. Here we demonstrate that these elements can affect expression of neighboring genes and present evidence that they are mobile. Together, our findings show that BOX elements enhance genetic diversity and genomic plasticity in Streptococcus pneumoniae.
摘要
100多个BOX元件随机分布在肺炎球菌基因组的基因间区域。在此，我们证明这些元件可影响邻近基因的表达，并提供证据表明它们具有移动性。我们的研究结果共同表明，BOX元件可增强肺炎链球菌的遗传多样性和基因组可塑性。
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2
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3
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