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BOX元件调节肺炎链球菌中的基因表达：对感受态发育微调的影响。

BOX elements modulate gene expression in Streptococcus pneumoniae: impact on the fine-tuning of competence development.

作者信息

Knutsen Eivind, Johnsborg Ola, Quentin Yves, Claverys Jean-Pierre, Håvarstein Leiv Sigve

机构信息

Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, As, Norway.

出版信息

J Bacteriol. 2006 Dec;188(23):8307-12. doi: 10.1128/JB.00850-06. Epub 2006 Sep 22.

DOI:10.1128/JB.00850-06
PMID:16997972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1698192/
Abstract

More than 100 BOX elements are randomly distributed in intergenic regions of the pneumococcal genome. Here we demonstrate that these elements can affect expression of neighboring genes and present evidence that they are mobile. Together, our findings show that BOX elements enhance genetic diversity and genomic plasticity in Streptococcus pneumoniae.

摘要

100多个BOX元件随机分布在肺炎球菌基因组的基因间区域。在此，我们证明这些元件可影响邻近基因的表达，并提供证据表明它们具有移动性。我们的研究结果共同表明，BOX元件可增强肺炎链球菌的遗传多样性和基因组可塑性。

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本文引用的文献

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Nucleic Acids Res. 2006 Feb 1;34(2):659-66. doi: 10.1093/nar/gkj472. Print 2006.
2
Effect of 5'-proximal elements on decay of a model mRNA in Bacillus subtilis.5'-近端元件对枯草芽孢杆菌中一个模型mRNA衰变的影响。
Mol Microbiol. 2005 Jul;57(2):484-95. doi: 10.1111/j.1365-2958.2005.04683.x.
3
Two separate quorum-sensing systems upregulate transcription of the same ABC transporter in Streptococcus pneumoniae.两个独立的群体感应系统上调肺炎链球菌中同一ABC转运蛋白的转录。
J Bacteriol. 2004 May;186(10):3078-85. doi: 10.1128/JB.186.10.3078-3085.2004.
4
The RNA degradosome and poly(A) polymerase of Escherichia coli are required in vivo for the degradation of small mRNA decay intermediates containing REP-stabilizers.大肠杆菌的RNA降解体和聚腺苷酸聚合酶在体内对于含有REP稳定子的小mRNA降解中间体的降解是必需的。
Mol Microbiol. 2004 Feb;51(3):777-90. doi: 10.1046/j.1365-2958.2003.03862.x.
5
RNA processing and degradation in Bacillus subtilis.枯草芽孢杆菌中的RNA加工与降解
Microbiol Mol Biol Rev. 2003 Jun;67(2):157-74, table of contents. doi: 10.1128/MMBR.67.2.157-174.2003.
6
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7
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Nucleic Acids Res. 2002 Oct 1;30(19):4216-21. doi: 10.1093/nar/gkf534.
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9
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