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心房颤动外科治疗的新时代:消融技术和消融灶对手术疗效的影响。

A new era in the surgical treatment of atrial fibrillation: the impact of ablation technology and lesion set on procedural efficacy.

作者信息

Melby Spencer J, Zierer Andreas, Bailey Marci S, Cox James L, Lawton Jennifer S, Munfakh Nabil, Crabtree Traves D, Moazami Nader, Huddleston Charles B, Moon Marc R, Damiano Ralph J

机构信息

Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine and Barnes-Jewish Hospital, St Louis, MO 63110, USA.

出版信息

Ann Surg. 2006 Oct;244(4):583-92. doi: 10.1097/01.sla.0000237654.00841.26.

Abstract

BACKGROUND/OBJECTIVE: While the Cox-Maze procedure remains the gold standard for the surgical treatment of atrial fibrillation (AF), the use of ablation technology has revolutionized the field. To simplify the procedure, our group has replaced most of the incisions with bipolar radiofrequency ablation lines. The purpose of this study was to examine results using bipolar radiofrequency in 130 patients undergoing a full Cox-Maze procedure, a limited Cox-Maze procedure, or pulmonary vein isolation alone.

METHODS

A retrospective review was performed of patients who underwent a Cox-Maze procedure (n = 100), utilizing bipolar radiofrequency ablation, a limited Cox-Maze procedure (n = 7), or pulmonary vein isolation alone (n = 23). Follow-up was available on 129 of 130 patients (99%).

RESULTS

Pulmonary vein isolation was confirmed by intraoperative pacing in all patients. Cross-clamp time in the lone Cox-Maze procedure patients was 44 +/- 21 minutes, and 104 +/- 42 minutes for the Cox-Maze procedure with a concomitant procedure, which was shortened considerably from our traditional cut-and-sew Cox-Maze procedure times (P < 0.05). There were 4 postoperative deaths in the Cox-Maze procedure group and 1 in the pulmonary vein isolation group. The mean follow-up was 13 +/- 10, 23 +/- 15, and 9 +/- 10 months for the Cox-Maze IV, the pulmonary vein isolation, and the limited Cox-Maze procedure groups, respectively. At last follow-up, freedom from AF was 90% (85 of 94), 86% (6 of 7), and 59% (10 of 17) in the in the Cox-Maze procedure group, limited Cox-Maze procedure group, and pulmonary vein isolation alone group, respectively.

CONCLUSIONS

The use of bipolar radiofrequency ablation to replace Cox-Maze incisions was safe and effective at controlling AF. Pulmonary vein isolation alone was much less effective, and should be used cautiously in this population.

摘要

背景/目的:虽然Cox迷宫手术仍是心房颤动(AF)外科治疗的金标准,但消融技术的应用彻底改变了该领域。为简化手术,我们团队已用双极射频消融线取代了大部分切口。本研究的目的是检查130例行完整Cox迷宫手术、有限Cox迷宫手术或仅行肺静脉隔离术的患者使用双极射频的结果。

方法

对行Cox迷宫手术(n = 100)、使用双极射频消融的有限Cox迷宫手术(n = 7)或仅行肺静脉隔离术(n = 23)的患者进行回顾性分析。130例患者中有129例(99%)获得随访。

结果

所有患者术中起搏均证实肺静脉隔离成功。单纯Cox迷宫手术患者的交叉夹闭时间为44±21分钟,联合其他手术的Cox迷宫手术患者为104±42分钟,较我们传统的切割缝合Cox迷宫手术时间大幅缩短(P < 0.05)。Cox迷宫手术组有4例术后死亡,肺静脉隔离组有1例。Cox迷宫IV组、肺静脉隔离组和有限Cox迷宫手术组的平均随访时间分别为13±10、23±15和9±10个月。在最后一次随访时,Cox迷宫手术组、有限Cox迷宫手术组和仅行肺静脉隔离术组的房颤-free率分别为90%(94例中的85例)、86%(7例中的6例)和59%(17例中的10例)。

结论

使用双极射频消融取代Cox迷宫切口在控制房颤方面安全有效。仅行肺静脉隔离术效果差得多,在该人群中应谨慎使用。

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本文引用的文献

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Irrigated radiofrequency ablation with transmurality feedback reliably produces Cox maze lesions in vivo.
Ann Thorac Surg. 2005 Dec;80(6):2263-70. doi: 10.1016/j.athoracsur.2005.06.017.
9
A multi-institutional experience with the CryoMaze procedure.一项关于冷冻迷宫手术的多机构经验。
Ann Thorac Surg. 2005 Sep;80(3):876-80; discussion 880. doi: 10.1016/j.athoracsur.2005.03.075.

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