帕金森运动障碍中的姿势控制、步态与多巴胺功能
Postural control, gait, and dopamine functions in parkinsonian movement disorders.
作者信息
Bohnen Nicolaas I, Cham Rakié
机构信息
Department of Radiology and Neurology, University of Michigan, 24 Frank Lloyd Wright Drive, Box 362, Ann Arbor, MI 48106, USA.
出版信息
Clin Geriatr Med. 2006 Nov;22(4):797-812, vi. doi: 10.1016/j.cger.2006.06.009.
Balance impairments and falls, which are common in patients who have parkinsonian movement disorders, are a serious threat to the health of these individuals. However, the underlying mechanisms cannot be fully explained by presynaptic dopaminergic denervation, because balance impairment is at least responsive to L-dopa therapy. This article reviews the latest clinically relevant literature relating postural control, gait, and dopamine in patients who have parkinsonian movement disorders.
平衡障碍和跌倒在帕金森氏运动障碍患者中很常见，对这些人的健康构成严重威胁。然而，潜在机制不能完全用突触前多巴胺能去神经来解释，因为平衡障碍至少对左旋多巴治疗有反应。本文综述了帕金森氏运动障碍患者中与姿势控制、步态和多巴胺相关的最新临床相关文献。
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