[从孕妇中分离出的无乳链球菌菌株的抗菌药敏性及血清型分布]

[Antimicrobial susceptibilities and serotype distribution of Streptococcus agalactiae strains isolated from pregnant women].

作者信息

Yenişehirli Gülgün, Bulut Yunus, Demirtürk Fazli, Calişkan A Cantuğ

机构信息

Gaziosmanpaşa Universitesi Tip Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dali, Tokat.

出版信息

Mikrobiyol Bul. 2006 Jul;40(3):155-60.

PMID:17001843

Abstract

Streptococcus agalactiae (Group B streptococcus, GBS) is an important cause of neonatal morbidity and mortality. The aim of this study was to determine the serotype distribution and antibiotic susceptibility patterns of GBS isolated from pregnant women. A total of 671 pregnant women were screened for vaginal carriage of GBS, and vaginal colonization rate was found to be 14.6%. All GBS isolates were susceptible to penicillin, vancomycin, chloramphenicol and ofloxacin. The rates of GBS resistance to tetracycline, erythromycin and clindamycin were 81.6%, 24.5% and 19.4%, respectively. The serotype distribution of GBS isolates was as follows in order of frequency; serotype III (33.7%), serotype Ib (24.5%), serotype V (18.4%), serotype Ia (7.1%), serotype IV (3.1%) and serotype II (2%). Eleven GBS isolates could not be serotyped by the antisera set used in the study.

摘要

无乳链球菌（B族链球菌，GBS）是新生儿发病和死亡的重要原因。本研究的目的是确定从孕妇中分离出的GBS的血清型分布和抗生素敏感性模式。共对671名孕妇进行了GBS阴道携带情况筛查，发现阴道定植率为14.6%。所有GBS分离株对青霉素、万古霉素、氯霉素和氧氟沙星敏感。GBS对四环素、红霉素和克林霉素的耐药率分别为81.6%、24.5%和19.4%。GBS分离株的血清型分布按频率依次如下：III型（33.7%）、Ib型（24.5%）、V型（18.4%）、Ia型（7.1%）、IV型（3.1%）和II型（2%）。11株GBS分离株无法通过本研究中使用的抗血清进行血清分型。