载脂蛋白对人脂肪组织脂蛋白脂肪酶活性的影响。
Effects of apolipoproteins on lipoprotein lipase activity of human adipose tissue.
作者信息
Ekman R, Nilsson-Ehle P
出版信息
Clin Chim Acta. 1975 Aug 18;63(1):29-35. doi: 10.1016/0009-8981(75)90374-5.
PMID:170020
Abstract
The effect of apolipoproteins isolated from HDL and VLDL on the activity of lipoprotein lipase (LPL) of adipose tissue was studied. The CII apoprotein was found to activate LPL. This activation was strongly inhibited by CI, AI (apo-Lp-Gln I), and the arginine-rich apoprotein, whereas AII and CIII exhibited a considerably lower inhibitor effect.
摘要
研究了从高密度脂蛋白（HDL）和极低密度脂蛋白（VLDL）中分离出的载脂蛋白对脂肪组织脂蛋白脂肪酶（LPL）活性的影响。发现载脂蛋白CII可激活LPL。这种激活作用受到载脂蛋白CI、AI（apo-Lp-Gln I）和富含精氨酸的载脂蛋白的强烈抑制，而载脂蛋白AII和CIII的抑制作用则低得多。
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