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前列腺增生症的累积患病率与良性前列腺增生的尸检患病率相符。

Cumulative prevalence of prostatism matches the autopsy prevalence of benign prostatic hyperplasia.

作者信息

Guess H A, Arrighi H M, Metter E J, Fozard J L

机构信息

Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill 27599-7400.

出版信息

Prostate. 1990;17(3):241-6. doi: 10.1002/pros.2990170308.

Abstract

The age-specific cumulative prevalence of clinically diagnosed prostatism among 1,057 generally healthy men followed for up to 30 years in the Baltimore Longitudinal Study of Aging was compared with the age-specific autopsy prevalence of pathologically defined benign prostatic hyperplasia (BPH) from a published compilation of five independent autopsy studies involving 1,075 prostates. Clinical prevalences based on medical histories and digital rectal examinations showed excellent agreement with autopsy prevalences at all ages. Despite the well-known lack of correspondence between prostatism and objective urologic evidence of BPH in individual patients, these results suggest that the proportion of the male population with clinically recognizable prostatism by a given age is about the same as the proportion with pathological evidence of BPH.

摘要

在巴尔的摩纵向衰老研究中,对1057名总体健康的男性进行了长达30年的随访,比较了不同年龄组临床诊断前列腺增生症的累积患病率,并与来自五项独立尸检研究(涉及1075个前列腺)的已发表汇编中病理定义的良性前列腺增生(BPH)的年龄特异性尸检患病率进行了比较。基于病史和直肠指检的临床患病率在所有年龄段都与尸检患病率显示出极好的一致性。尽管众所周知,在个体患者中前列腺增生症与BPH的客观泌尿外科证据之间缺乏对应关系,但这些结果表明,在特定年龄具有临床可识别前列腺增生症的男性人口比例与具有BPH病理证据的比例大致相同。

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