一种抗糖尿病植物甜杆草的植物化学与抗菌研究

Phytochemical and antimicrobial study of an antidiabetic plant: Scoparia dulcis L.

作者信息

Latha M, Ramkumar K M, Pari L, Damodaran P N, Rajeshkannan V, Suresh T

机构信息

Department of Biochemistry, Faculty of Science, Annamalai University, Annamalainagar, India.

出版信息

J Med Food. 2006 Fall;9(3):391-4. doi: 10.1089/jmf.2006.9.391.

DOI:10.1089/jmf.2006.9.391

PMID:17004904

Abstract

The antimicrobial and antifungal effects of different concentrations of chloroform/methanol fractions of Scoparia dulcis were investigated. The isolated fractions were tested against different bacteria like Salmonella typhii, Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, and Proteus vulgaris and fungal strains such as Alternaria macrospora, Candida albicans, Aspergillus niger, and Fusarium oxysporum. The isolated fractions exhibited significant antimicrobial and antifungal activity against all the tested organisms compared with respective reference drugs. The isolated fractions of S. dulcis showed properties like antimicrobial and antifungal activities that will enable researchers in turn to look for application-oriented principles.

摘要

研究了甜地锦不同浓度氯仿/甲醇提取物的抗菌和抗真菌作用。对分离得到的提取物针对不同细菌如伤寒沙门氏菌、金黄色葡萄球菌、大肠杆菌、枯草芽孢杆菌、铜绿假单胞菌和普通变形杆菌以及真菌菌株如大孢链格孢、白色念珠菌、黑曲霉和尖孢镰刀菌进行了测试。与各自的参考药物相比，分离得到的提取物对所有测试生物均表现出显著的抗菌和抗真菌活性。甜地锦分离得到的提取物显示出抗菌和抗真菌活性等特性，这将使研究人员进而寻找应用型原理。