Schlag J, Schlag-Rey M
Department of Anatomy and Cell Biology, Medical School, University of California, Los Angeles 90024.
Trends Neurosci. 1990 Oct;13(10):410-5. doi: 10.1016/0166-2236(90)90122-q.
Saccades are fast eye movements by which objects of interest are sought and captured. Their brevity means that they can often be executed within the time taken by visual impulses to reach the brain. Microstimulation, used in conjunction with single-unit recording, has become a powerful tool for analysing the role of central visuomotor structures in producing accurate saccades. This review presents the rationale of a test in which saccades are artificially elicited (evoked) while the eyes are moving. The presumed role in saccade production played by stimulated local neurons is inferred from the way trajectories of evoked saccades are deviated. The results suggest that the forebrain structures tested designate a goal expressed in retinocentric coordinates. To take into account an eye displacement that occurs during visual processing, the goal location must be recomputed; in this article, current views on how this might be accomplished are discussed in relation to observations made by unit recording.
扫视是一种快速的眼球运动，通过它来寻找和捕捉感兴趣的物体。其短暂性意味着它们通常可以在视觉冲动到达大脑所需的时间内执行。微刺激与单神经元记录结合使用，已成为分析中枢视觉运动结构在产生准确扫视中作用的有力工具。本综述介绍了一种测试的基本原理，即在眼睛移动时人工诱发（引发）扫视。从诱发扫视轨迹的偏离方式推断出受刺激的局部神经元在扫视产生中可能扮演的角色。结果表明，所测试的前脑结构指定了以视网膜中心坐标表示的目标。为了考虑视觉处理过程中发生的眼球位移，必须重新计算目标位置；在本文中，结合单神经元记录的观察结果，讨论了关于如何实现这一点的当前观点。
