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Thermodynamical model of indefinite mixed association of two components and NMR data analysis for caffeine-AMP interaction.

作者信息

Weller K, Schütz H, Petri I

机构信息

Akademie der Wissenschaften der DDR, Zentralinstitut für Mikrobiologie und experimentelle Therapie, DDR-69 Jena, G.D.R.

出版信息

Biophys Chem. 1984 Jun;19(4):289-98. doi: 10.1016/0301-4622(84)87012-x.

DOI:10.1016/0301-4622(84)87012-x
PMID:17005143
Abstract

This paper describes the model used to estimate the parameters of caffeine-AMP interactions from corresponding 1H-NMR measurements and some methods of data analysis by which the applicability of the model has been checked. The model of mixed association is applicable to a mixture of any two substances A and C which exhibit indefinite aggregates in both self-association and mixed association. In aggregates, only nearest neighbour interaction is assumed. The model is described by three equilibrium constants: Kaa and Kcc (for self-association of A, or C, respectively), and Kac (for mixed association).

摘要

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