DNA测序在诊断移植受者中由两种真菌（委内瑞拉拟顶孢霉和一种盘多毛孢属真菌）引起的混合感染方面的局限性。
Limitations of DNA sequencing for diagnosis of a mixed infection by two fungi, Phaeoacremonium venezuelense and a Plectophomella sp., in a transplant recipient.
作者信息
Guarro Josep, Silvestre Agenor Messias, Verkley Gerard, Cano Josep, Gompertz Olga Fischman, Gené Josepa, Ogawa Marília Marufuji, Tomimori-Yamashita Jane, Teixeira Solange Pistori, de Almeida Fernando Augusto
机构信息
Unitat de Micologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, 43201 Reus, Spain.
出版信息
J Clin Microbiol. 2006 Nov;44(11):4279-82. doi: 10.1128/JCM.00496-06. Epub 2006 Sep 27.
Abstract
We describe a rare case of a subcutaneous infection by both Phaeoacremonium venezuelense and Plectophomella sp. in a Brazilian male. Sequencing of a beta-tubulin gene fragment allowed us to confirm the identification of the former. However, a similar procedure of sequencing rRNA gene fragments was not useful for the identification of the latter fungus.
摘要
我们描述了一名巴西男性同时感染委内瑞拉拟色串孢菌和一种盘多毛孢属真菌的罕见病例。对β-微管蛋白基因片段进行测序使我们能够确认前者的鉴定。然而，对核糖体RNA基因片段进行类似的测序程序对鉴定后者真菌并无帮助。
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