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从美国住院患者中分离出的病原体的抗菌药敏性以及新型甘氨酰环素类抗菌药物替加环素的体外活性。

Antimicrobial susceptibility among pathogens collected from hospitalized patients in the United States and in vitro activity of tigecycline, a new glycylcycline antimicrobial.

作者信息

Waites Ken B, Duffy Lynn B, Dowzicky Michael J

机构信息

Section of Clinical Microbiology, University of Alabama at Birmingham, Birmingham, AL 35249, USA.

出版信息

Antimicrob Agents Chemother. 2006 Oct;50(10):3479-84. doi: 10.1128/AAC.00210-06.

Abstract

The activities of tigecycline and comparators against isolates collected from 76 U.S. centers between January 2004 and September 2005 were assessed. Tigecycline MIC(90)s were < or =2 microg/ml for Klebsiella pneumoniae, Klebsiella oxytoca, Escherichia coli, Enterobacter aerogenes, Enterobacter cloacae, Serratia marcescens, Acinetobacter baumannii, Staphylococcus aureus, Enterococcus faecalis, Enterococcus faecium, and Streptococcus agalactiae.

摘要

对2004年1月至2005年9月间从美国76个中心收集的分离菌株进行了替加环素及对照药物活性评估。肺炎克雷伯菌、产酸克雷伯菌、大肠埃希菌、产气肠杆菌、阴沟肠杆菌、粘质沙雷菌、鲍曼不动杆菌、金黄色葡萄球菌、粪肠球菌、屎肠球菌和无乳链球菌的替加环素MIC(90)≤2μg/ml。

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