Brueggemann Angela B
Department of Zoology, University of Oxford, Oxford, UK.
Pediatr Infect Dis J. 2006 Oct;25(10):969-73. doi: 10.1097/01.inf.0000239365.60595.d5.
Antibiotic resistance is a continually increasing problem that has, to a greater or lesser extent, affected virtually every area of the world. The scientific literature is abundant with papers related to antibiotics and antibiotic resistance. Many excellent papers and reviews have been published during the past few years, and the literature base continues to expand at rapid speed. This review is meant to provide a recent update on antibiotic resistance among respiratory and enteric pathogens, with a focus on infections in children. Not a small task, but this paper is not meant to be exhaustive. Rather, the intention is to highlight the key antibiotics and antibiotic resistance mechanisms that are currently the most relevant to pediatrics. The most recently published literature is used wherever possible, and the reader is encouraged to explore specific topics of interest further by reviewing the referenced literature.
抗生素耐药性是一个日益严重的问题，或多或少地影响了世界上几乎每个地区。科学文献中有大量与抗生素和抗生素耐药性相关的论文。在过去几年中发表了许多优秀的论文和综述，而且文献库仍在迅速扩大。本综述旨在提供有关呼吸道和肠道病原体抗生素耐药性的最新情况，重点关注儿童感染。这并非一项轻松的任务，但本文并非意在详尽无遗。相反，其目的是突出当前与儿科最为相关的关键抗生素及抗生素耐药机制。只要有可能，就使用最新发表的文献，并鼓励读者通过查阅参考文献进一步探索感兴趣的特定主题。
