持续硬膜外注射氢吗啡酮用于开胸术后镇痛

Continuous epidural hydromorphone for postthoracotomy pain relief.

作者信息

Brodsky J B, Chaplan S R, Brose W G, Mark J B

机构信息

Department of Anesthesia, Stanford University School of Medicine, California.

出版信息

Ann Thorac Surg. 1990 Dec;50(6):888-93. doi: 10.1016/0003-4975(90)91113-p.

DOI:10.1016/0003-4975(90)91113-p

PMID:1700682

Abstract

Forty-four patients were treated with a continuous infusion of lumbar epidural hydromorphone (0.05%) after thoracic operations. Postoperatively, visual analog pain scores were obtained. On postoperative day 1 and 2, more than 90% of the patients experienced either no pain (visual analog pain scale = 0) or mild pain (visual analog pain score = 1 to 3) at rest. The incidence of side effects (hypoventilation, pruritus, and nausea) was less than reported with other epidurally administered opioids. Continuous infusion of lumbar epidural hydromorphone produced safe, predictable analgesia after thoracotomy.

摘要

44例患者在胸科手术后接受持续输注腰椎硬膜外氢吗啡酮（0.05%）治疗。术后获得视觉模拟疼痛评分。在术后第1天和第2天，超过90%的患者在静息时无疼痛（视觉模拟疼痛量表=0）或轻度疼痛（视觉模拟疼痛评分=1至3）。副作用（通气不足、瘙痒和恶心）的发生率低于其他硬膜外给予阿片类药物的报道。持续输注腰椎硬膜外氢吗啡酮在开胸术后产生了安全、可预测的镇痛效果。