Mansouri Behzad, Hess Robert F
McGill Vision Research Unit, 687 Pine Avenue West, Rm. H4-14, Montreal, Que., Canada H3A 1A1.
Vision Res. 2006 Nov;46(24):4104-17. doi: 10.1016/j.visres.2006.07.017. Epub 2006 Sep 27.
Some studies have reported deficits in amblyopia for global form and motion integration, whereas other studies have shown global integration of form and motion information to be normal in amblyopia. Here, we attempt to resolve this discrepancy by showing that amblyopes only exhibit selective performance deficits on global tasks that contain noise as well as signal. We hypothesized that signal integration is normal, but noise segregation is not. We used comparable global orientation and motion direction discrimination tasks to measure integration performance in the presence of controlled amounts of pedestal noise (i.e., elements whose orientations or directions were randomly selected). We modelled the performance using an equivalent noise model, which has the parameters of internal noise and number of samples. Our results show that amblyopic eyes can integrate form (i.e., orientation) and motion information (i.e., motion direction) similarly to normals when all the information is signal (i.e., no pedestal noise). However, introducing pedestal noise perturbs the performance of the amblyopic eyes significantly more than that of the normal eyes.
一些研究报告称弱视患者在全局形状和运动整合方面存在缺陷，而其他研究则表明弱视患者的形状和运动信息全局整合是正常的。在此，我们试图通过表明弱视患者仅在包含噪声和信号的全局任务中表现出选择性性能缺陷来解决这一差异。我们假设信号整合是正常的，但噪声分离不正常。我们使用了可比的全局方向和运动方向辨别任务来测量在存在可控量的基座噪声（即方向或方向被随机选择的元素）情况下的整合性能。我们使用具有内部噪声和样本数量参数的等效噪声模型对性能进行建模。我们的结果表明，当所有信息都是信号（即无基座噪声）时，弱视眼能够与正常眼类似地整合形状（即方向）和运动信息（即运动方向）。然而，引入基座噪声对弱视眼性能的干扰明显大于对正常眼的干扰。
