Davari Hamid R, Yarmohammadi Hooman, Malekhosseini Seyed A, Salahi Heshmatollah, Bahador Ali, Salehipour Mehdi
Division of Surgery, Faghihi Hospital, Shiraz, Iran.
Int J Urol. 2006 Oct;13(10):1271-5. doi: 10.1111/j.1442-2042.2006.01539.x.
To present the urological complications of renal transplantations performed in the last 14 years at one center and to briefly explain a modified method of Lich-Gregoir ureteroneocystostomy.
The data of 980 patients receiving kidney transplants at the authors' institution from April 1991 to February 2004 were reviewed in a retrospective prospective study. In particular, surgical techniques and urological complications were noted.
A total of 980 patients had received kidney transplantation. Extravesical ureteroneocystostomy (Lich-Gregoir method) was used in the first 480 patients (group A). In the subsequent 500 patients, the authors' modified method of extravesical ureteroneocystostomy, using single layer anastomosis and small feeding tubes as stent, was used (group B). Overall urological complication rate was 2.8% (28 patients), including leakage (13 patients, 1.3%), stenosis (seven, 0.7%), obstruction (one, 0.1%), distal ureter necrosis (four, 0.4%), pelvocalyceal fistula (two, 0.2%) and implantation of ureter into the peritoneum (one, 0.1%). Urological complications were significantly more common in group A compared to group B (16, 3.3% and 9, 1.8%, respectively; P < 0.05).
Preserving the adventitia, fat and blood supply of the ureter by delicate dissection of the ureter during donor nephrectomy, short ureters, and fixation of the adventitia, fat and blood supply of the ureter to the bladder wall, to prevent kinking or twisting, are important factors in decreasing urological complications. Additionally, the authors' method of ureteroneocystostomy is also effective in decreasing the incidence of ureteric complications.
介绍某中心过去14年肾移植的泌尿外科并发症,并简要阐述改良的利奇-格雷戈尔输尿管膀胱吻合术。
对1991年4月至2004年2月在作者所在机构接受肾移植的980例患者的数据进行回顾性前瞻性研究。特别记录了手术技术和泌尿外科并发症。
共有980例患者接受了肾移植。前480例患者采用膀胱外输尿管膀胱吻合术(利奇-格雷戈尔法)(A组)。在随后的500例患者中,采用了作者改良的膀胱外输尿管膀胱吻合术,即单层吻合并使用小喂养管作为支架(B组)。总体泌尿外科并发症发生率为2.8%(28例患者),包括漏尿(13例,1.3%)、狭窄(7例,0.7%)、梗阻(1例,0.1%)、输尿管远端坏死(4例,0.4%)、肾盂盏瘘(2例,0.2%)和输尿管植入腹膜(1例,0.1%)。A组的泌尿外科并发症明显比B组更常见(分别为16例,3.3%和9例,1.8%;P<0.05)。
在供肾切除术中通过精细解剖输尿管来保留输尿管的外膜、脂肪和血供,对于短输尿管,以及将输尿管的外膜、脂肪和血供固定于膀胱壁以防止扭结或扭曲,是降低泌尿外科并发症的重要因素。此外,作者的输尿管膀胱吻合术方法在降低输尿管并发症发生率方面也有效。