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带支架的利奇-格雷戈尔输尿管膀胱吻合术:病例系列报告及成本效益分析

Stented Lich-Gregoir ureteroneocystostomy: case series report and cost-effectiveness analysis.

作者信息

Mangus R S, Haag B W, Carter C B

机构信息

Indiana University School of Medicine, Methodist Hospital Renal Transplant Program, Indianapolis, Indiana 46202, USA.

出版信息

Transplant Proc. 2004 Dec;36(10):2959-61. doi: 10.1016/j.transproceed.2004.10.061.

Abstract

UNLABELLED

Extravesical ureteroneocystostomy to reestablish urinary tract continuity in renal transplantation has been examined through a meta-analysis of more than 14,000 kidney transplants leading to the finding that stented anastomosis was associated with a lower urologic complication rate compared with nonstented anastomoses. Fourteen stents must be used to prevent one urologic complication. We now report the urologic complication rate in our case series in which a stented Lich-Gregoir anastomosis was routinely utilized. We present a cost-effectiveness analysis regarding the usage of ureteral stents.

METHODS

The records of 395 consecutive renal transplants were reviewed. Minimum follow-up time was 6 months. The standard anastomosis was a Lich-Gregoir with a 6- or 8-F 12- or 14-cm J-J stent. Monitored urologic complications included postoperative vesicoureteral leak or ureteral necrosis, obstruction or stricture, or clinically significant hematuria. Charges in 2004 US dollars were reported by the hospital accounting office.

RESULTS

Four urologic complications were noted-three leaks and one stricture (complication rate of 1.0%). There were no stent-related complications requiring reoperation. There were no cases in which the urologic complication led to graft loss or patient death. Total charges associated with stent use were $1,087 per patient, or $15,218 per urologic complication prevented.

CONCLUSIONS

The urologic complication rate in this case series is similar to the five previously published randomized trials, as well as our previously published meta-analysis. These results support the routine use of a ureteral stent. Our analysis suggests that stent use is cost effective.

摘要

未标注

通过对超过14000例肾移植病例的荟萃分析,对膀胱外输尿管膀胱再植术重建肾移植尿路连续性进行了研究,结果发现与无支架吻合术相比,有支架吻合术的泌尿系统并发症发生率更低。必须使用14个支架才能预防1例泌尿系统并发症。我们现在报告我们病例系列中使用有支架的利奇 - 格雷戈尔吻合术时的泌尿系统并发症发生率。我们还提供了关于输尿管支架使用的成本效益分析。

方法

回顾了395例连续肾移植病例的记录。最短随访时间为6个月。标准吻合术为利奇 - 格雷戈尔吻合术,使用6或8F、12或14厘米的J型 - J型支架。监测的泌尿系统并发症包括术后膀胱输尿管漏或输尿管坏死、梗阻或狭窄,或具有临床意义的血尿。医院会计办公室报告了以2004年美元计算的费用。

结果

发现4例泌尿系统并发症——3例漏和1例狭窄(并发症发生率为1.0%)。没有需要再次手术的与支架相关的并发症。没有泌尿系统并发症导致移植肾丢失或患者死亡的病例。与使用支架相关的总费用为每位患者1087美元,或预防1例泌尿系统并发症的费用为15218美元。

结论

本病例系列中的泌尿系统并发症发生率与之前发表的5项随机试验以及我们之前发表的荟萃分析结果相似。这些结果支持常规使用输尿管支架。我们的分析表明使用支架具有成本效益。

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