意大利一家城市精神科单位中丙型肝炎病毒阳性患者的特征。
Characteristics of HCV positive patients in an Italian urban psychiatric unit.
作者信息
Raja Michele, Azzoni Antonella, Pucci Daniela
机构信息
Servizio Psichiatrico di Diagnosi e Cura, Ospedale Santo Spirito, Rome, Italy.
出版信息
Clin Pract Epidemiol Ment Health. 2006 Oct 1;2:26. doi: 10.1186/1745-0179-2-26.
OBJECTIVES
- to assess the prevalence of hepatitis C virus (HCV) infection in a population of acute psychiatric in-patients; 2) to find out relationships between HCV comorbidity and clinical features of psychiatric patients.
METHODS
Prospective observational study in a 6-year period.
RESULTS
2396 cases (1492 patients) were admitted in the considered period. Forty-two patients (2.8%) were affected by HCV infection. HCV infection was more frequent in patients with less years of education, lower social class, lower last year best Global Assessment of Functioning score, more hostile or violent behavior in hospital, with a lifetime history of previous suicide attempt, and with substance-related disorders.
CONCLUSION
HCV infection in psychiatric patients constitutes a major threat to the health of psychiatric patients and is related with unfavorable social background, worse global functioning, hostile or violent behavior, substance-related disorders. It appears also to be a significant risk of suicidal behavior.
目的
1）评估急性精神科住院患者群体中丙型肝炎病毒（HCV）感染的患病率；2）找出HCV合并症与精神科患者临床特征之间的关系。
方法
为期6年的前瞻性观察研究。
结果
在研究期间共收治2396例（1492名患者）。42例患者（2.8%）感染HCV。HCV感染在受教育年限较少、社会阶层较低、去年全球功能评估最佳得分较低、在医院有更多敌对或暴力行为、有过自杀未遂终生史以及患有物质相关障碍的患者中更为常见。
结论
精神科患者中的HCV感染对精神科患者的健康构成重大威胁，并且与不利的社会背景、较差的整体功能、敌对或暴力行为、物质相关障碍有关。它似乎也是自杀行为的一个重要风险因素。
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