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抗逆转录病毒疗法:皮肤科医生入门指南。

Antiretroviral therapy: a primer for dermatologists.

作者信息

Kim H Nina, Harrington Robert D

机构信息

Division of Allergy and Infectious Diseases, University of Washington School of Medicine, 325 Ninth Avenue, Seattle WA 98104, USA.

出版信息

Dermatol Clin. 2006 Oct;24(4):537-47, vii. doi: 10.1016/j.det.2006.06.012.

Abstract

Combination antiretroviral therapy (ART) has transformed the care of individuals who have HIV infection. Effective ART has resulted in dramatic reductions in mortality, hospitalization rates, and the development of AIDS-defining illnesses. This article discusses the variety of agents that can comprise an effective ART regimen, focusing on the basic principles of ART, the indications for initiating ART in treatment-naive individuals who have established HIV infection, and the challenges associated with the use of antiretroviral medications.

摘要

联合抗逆转录病毒疗法(ART)已经改变了对感染艾滋病毒个体的护理。有效的ART已使死亡率、住院率以及艾滋病界定疾病的发生率大幅降低。本文讨论了可构成有效ART方案的各类药物,重点关注ART的基本原则、对已确诊感染艾滋病毒的初治个体启动ART的指征,以及与使用抗逆转录病毒药物相关的挑战。

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