Turetsky B, Raz J, Fein G
Medical College of Pennsylvania and Eastern Pennsylvania Psychiatric Institute, Philadelphia.
Electroencephalogr Clin Neurophysiol. 1990 Dec;76(6):540-56. doi: 10.1016/0013-4694(90)90004-4.
A number of procedures have been employed to decompose recorded scalp potential wave forms into their hypothesized constituent elements. The shortcomings of the various decomposition methods (principal components analysis, topographic components modeling, inverse dipole localization and spatio-temporal dipole modeling) are reviewed and a new dipole components model, which incorporates the strengths of the topographic components model and the spatio-temporal dipole model, is presented. This model decomposes ERPs into subcomponents reflecting the activity of dipole sources with location and orientation fixed across subjects and with the temporal activity of each dipole modeled as a decaying sinusoid. The requirement that the equivalent dipole generators be the same across subjects and experimental conditions permits analysis of inter-group differences and of the effects of experimental variables. An application of the model to data from a 3-tone auditory target detection task is presented, and equivalent dipole sources of the components of the auditory evoked potential are described. Assumptions inherent in the model, as well as practical obstacles to its widespread implementation, are discussed.
人们采用了多种方法将记录的头皮电位波形分解为其假设的组成成分。本文回顾了各种分解方法（主成分分析、地形成分建模、偶极子定位和时空偶极子建模）的缺点，并提出了一种新的偶极子成分模型，该模型结合了地形成分模型和时空偶极子模型的优点。该模型将事件相关电位分解为子成分，这些子成分反映了偶极子源的活动，其位置和方向在不同受试者之间固定，并且每个偶极子的时间活动被建模为衰减的正弦波。要求等效偶极子发生器在不同受试者和实验条件下相同，这允许分析组间差异和实验变量的影响。本文展示了该模型在三音听觉目标检测任务数据中的应用，并描述了听觉诱发电位成分的等效偶极子源。同时还讨论了该模型固有的假设以及其广泛应用的实际障碍。
