Giard M H, Perrin F, Echallier J F, Thévenet M, Froment J C, Pernier J
Brain Signals and Processes Laboratory, INSERM-U280, Lyon, France.
Electroencephalogr Clin Neurophysiol. 1994 May;92(3):238-52. doi: 10.1016/0168-5597(94)90067-1.
This study reports a combined scalp current density (SCD) and dipole model analysis of the N1 wave of the auditory event-related potentials evoked by 1 kHz tone bursts delivered every second. The SCD distributions revealed: (i) a sink and a source of current reversing in polarity at the inferotemporal level of each hemiscalp, compatible with neural generators in and around the supratemporal plane of the auditory cortex, as previously reported; and (ii) bilateral current sinks over frontal areas. Consistently, dynamic dipole model analysis showed that generators in and outside the auditory cortex are necessary to account for the observed current fields between 65 and 140 msec post stimulus. The frontal currents could originate from the motor cortex, the supplementary motor area and/or the cingulate gyrus. The dissociation of an exogenous, obligatory frontal component from the sensory-specific response in the auditory N1 suggests that parallel processes served by distinct neural systems are activated during acoustic stimulation. Implications for recent models of auditory processing are discussed.
本研究报告了对每秒呈现一次的1千赫短纯音诱发的听觉事件相关电位N1波进行头皮电流密度（SCD）和偶极子模型联合分析的结果。SCD分布显示：（i）在每个半侧头皮的颞下水平，有一个电流汇和一个电流源，其极性反转，这与先前报道的听觉皮层颞上平面及其周围的神经发生器一致；（ii）额叶区域存在双侧电流汇。同样，动态偶极子模型分析表明，为了解释刺激后65至140毫秒之间观察到的电流场，听觉皮层内外的发生器都是必要的。额叶电流可能起源于运动皮层、辅助运动区和/或扣带回。听觉N1中来自感觉特异性反应的外源性、强制性额叶成分的分离表明，在声音刺激过程中，由不同神经系统服务的平行过程被激活。文中讨论了其对近期听觉处理模型的意义。
