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预测 Gustilo IIIA型和IIIB型开放性胫骨骨折保肢及预后的评分系统

A score for predicting salvage and outcome in Gustilo type-IIIA and type-IIIB open tibial fractures.

作者信息

Rajasekaran S, Naresh Babu J, Dheenadhayalan J, Shetty A P, Sundararajan S R, Kumar M, Rajasabapathy S

机构信息

Department of Orthopaedics, Ganga Hospital, Ramnagar, Coimbatore 641009, India.

出版信息

J Bone Joint Surg Br. 2006 Oct;88(10):1351-60. doi: 10.1302/0301-620X.88B10.17631.

Abstract

Limb-injury severity scores are designed to assess orthopaedic and vascular injuries. In Gustilo type-IIIA and type-IIIB injuries they have poor sensitivity and specificity to predict salvage or outcome. We have designed a trauma score to grade the severity of injury to the covering tissues, the bones and the functional tissues, grading the three components from one to five. Seven comorbid conditions known to influence the management and prognosis have been given a score of two each. The score was validated in 109 consecutive open injuries of the tibia, 42 type-IIIA and 67 type-IIIB. The total score was used to assess the possibilities of salvage and the outcome was measured by dividing the injuries into four groups according to their scores as follows: group I scored less than 5, group II 6 to 10, group III 11 to 15 and group IV 16 or more. A score of 14 to indicate amputation had the highest sensitivity and specificity. Our trauma score compared favourably with the Mangled Extremity Severity score in sensitivity (98% and 99%), specificity (100% and 17%), positive predictive value (100% and 97.5%) and negative predictive value (70% and 50%), respectively. A receiver-operating characteristic curve constructed for 67 type-IIIB injuries to assess the efficiency of the scores to predict salvage, showed that the area under the curve for this score was better (0.988 (+/- 0.013 SEM)) than the Mangled Extremity Severity score (0.938 (+/- 0.039 SEM)). All limbs in group IV and one in group III underwent amputation. Of the salvaged limbs, there was a significant difference in the three groups for the requirement of a flap for wound cover, the time to union, the number of surgical procedures required, the total days as an in-patient and the incidence of deep infection (p < 0.001 for all). The individual scores for covering and functional tissues were also found to offer specific guidelines in the management of these complex injuries. The scoring system was found to be simple in application and reliable in prognosis for both limb-salvage and outcome measures in type-IIIA and type-IIIB open injuries of the tibia.

摘要

肢体损伤严重程度评分旨在评估骨科和血管损伤情况。在 Gustilo IIIA型和IIIB型损伤中,它们对预测保肢或预后的敏感性和特异性较差。我们设计了一种创伤评分,用于对覆盖组织、骨骼和功能组织的损伤严重程度进行分级,将这三个部分从1到5级进行评分。已知会影响治疗和预后的七种合并症,每种给予2分。该评分在109例连续的胫骨开放性损伤中得到验证,其中42例为IIIA型,67例为IIIB型。总评分用于评估保肢的可能性,根据评分将损伤分为四组来衡量预后,具体如下:I组评分低于5分,II组6至10分,III组11至15分,IV组16分及以上。以14分作为截肢指征,其敏感性和特异性最高。我们的创伤评分在敏感性(分别为98%和99%)、特异性(分别为100%和17%)、阳性预测值(分别为100%和97.5%)和阴性预测值(分别为70%和50%)方面与肢体毁损伤严重程度评分相比具有优势。为67例IIIB型损伤构建的受试者工作特征曲线,用于评估评分预测保肢的效率,结果显示该评分的曲线下面积(0.988(±0.013标准误))优于肢体毁损伤严重程度评分(0.938(±0.039标准误))。IV组的所有肢体和III组的1例肢体均接受了截肢手术。在保肢的肢体中,三组在伤口覆盖所需皮瓣、愈合时间、所需手术次数、住院总天数以及深部感染发生率方面存在显著差异(所有p<0.001)。还发现覆盖组织和功能组织的单项评分在这些复杂损伤的治疗中提供了具体指导。该评分系统在应用中简单易行,对于胫骨IIIA型和IIIB型开放性损伤的保肢和预后评估在预后方面是可靠的。

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