Gupta A, Pollock R, Cannon S R, Briggs T W R, Skinner J, Blunn G
Department of Orthopaedic Oncology, Royal National Orthopaedic Hospital, Stanmore, Middlesex, HA7 4LP, UK.
J Bone Joint Surg Br. 2006 Oct;88(10):1367-72. doi: 10.1302/0301-620X.88B10.17756.
We used a knee-sparing distal femoral endoprosthesis in young patients with malignant bone tumours of the distal femur in whom it was possible to resect the tumour and to preserve the distal femoral condyles. The proximal shaft of the endoprosthesis had a coated hydroxyapatite collar, while the distal end had hydroxyapatite-coated extracortical plates to secure it to the small residual femoral condylar fragment. We reviewed the preliminary results of this endoprosthesis in eight patients with primary bone tumours of the distal femur. Their mean age at surgery was 17.years (14 to 21). The mean follow-up was 24 months (20 to 31). At final follow-up the mean flexion at the knee was 102 degrees (20 degrees to 120 degrees) and the mean Musculoskeletal Tumour Society score was 80% (57% to 96.7%). There was excellent osteointegration at the prosthesis-proximal bone interface with formation of new bone around the hydroxyapatite collar. The prosthesis allowed preservation of the knee and achieved a good functional result. Formation of new bone and remodelling at the interface make the implant more secure. Further follow-up is required to determine the long-term structural integrity of the prosthesis.
我们对股骨远端恶性骨肿瘤的年轻患者使用了保留膝关节的股骨远端假体,这些患者有可能切除肿瘤并保留股骨远端髁。假体的近端有一个涂层羟基磷灰石环,而远端有羟基磷灰石涂层的皮质外板,以将其固定到小的残余股骨髁碎片上。我们回顾了这种假体在8例股骨远端原发性骨肿瘤患者中的初步结果。他们手术时的平均年龄为17岁(14至21岁)。平均随访时间为24个月(20至31个月)。在最后随访时,膝关节的平均屈曲度为102度(20度至120度),肌肉骨骼肿瘤学会平均评分为80%(57%至96.7%)。在假体-近端骨界面处有良好的骨整合,在羟基磷灰石环周围形成了新骨。该假体能够保留膝关节并取得了良好的功能结果。界面处新骨的形成和重塑使植入物更加稳固。需要进一步随访以确定假体的长期结构完整性。