Efremidou Eleni I, Liratzopoulos Nikolaos, Papageorgiou Michalis S, Romanidis Konstantinos
1st Surgical Department of the Medical School of University General Hospital, Dragana, 68100 Alexandroupolis, Greece.
J Gastrointestin Liver Dis. 2006 Sep;15(3):297-9.
A case of perforated gastrointestinal stromal tumor (GIST) of small intestine causing acute abdomen is described, with a brief review of the literature. A male patient presented with symptoms of acute abdomen. After evaluation, a laparotomy was performed, where perforation of a tumor in the ileum was found. The perforated part along with the tumor was resected and the cytopathological examination showed that the tumor was GIST. Postoperatively, the patient received treatment, using imatinib. Gastrointestinal stromal tumors are relatively rare and often present with vague symptoms. Their first clinical manifestation as acute abdomen due to their perforation is extremely rare. In emergency laparotomy, a R0 resection is required and adjuvant therapy with imatinib must be considered.
本文描述了一例小肠穿孔性胃肠道间质瘤(GIST)导致急腹症的病例,并对相关文献进行简要回顾。一名男性患者出现急腹症症状。经评估后进行了剖腹手术,术中发现回肠肿瘤穿孔。切除穿孔部分及肿瘤,细胞病理学检查显示该肿瘤为GIST。术后患者接受了伊马替尼治疗。胃肠道间质瘤相对罕见,症状往往不明确。其因穿孔首次临床表现为急腹症极为罕见。在急诊剖腹手术中,需要进行R0切除,且必须考虑使用伊马替尼进行辅助治疗。