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[皮肤淋巴增殖性疾病和卡波西肉瘤患者的干扰素状态]

[The interferon status of patients with lymphoproliferative diseases of the skin and Kaposi's sarcoma].

作者信息

Faradzhev Z G, Samsonov V A, Parfenova T M, Malinovskaia V V

出版信息

Vestn Dermatol Venerol. 1990(7):4-7.

PMID:1701592
Abstract

Differences in the interferon status of various nature were revealed in patients with lymphoproliferative diseases of the skin and with Kaposi's sarcoma, whose interferon system was examined in respect of its three major parameters. Such data are a sufficient basis for the correction of the detected changes by interferon preparations combined with other chemical drugs. Two parameters of the interferon system may serve as criteria of interferon therapy efficacy: increased alpha-interferon level and, more so, normalization of the gamma component of interferon production, tested by the gamma parameter.

摘要

在对皮肤淋巴增殖性疾病患者和卡波西肉瘤患者的干扰素系统的三个主要参数进行检查时,发现了不同性质的干扰素状态差异。这些数据足以作为通过干扰素制剂与其他化学药物联合来纠正检测到的变化的依据。干扰素系统的两个参数可作为干扰素治疗效果的标准:α干扰素水平升高,更重要的是,通过γ参数检测的干扰素产生的γ成分正常化。

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