获得性免疫缺陷综合征和卡波西肉瘤患者体内的干扰素及干扰素灭活剂。初步报告。
Interferon and interferon inactivators in patients with acquired immune deficiency syndrome and Kaposi's sarcoma. A preliminary report.
作者信息
Ikossi-O'Connor M G, Ambrus J L, West T, Lillie M A, Milgrom H, Chadha K C
出版信息
Res Commun Chem Pathol Pharmacol. 1984 Aug;45(2):271-7.
PMID:6207572
Abstract
The interferon system has been implicated in the diagnosis and potential treatment of acquired immune deficiency syndrome (AIDS). In our study of AIDS patients we have identified the presence of circulating serum interferon inactivator(s). These interferon inactivators were not detected in AIDS prodrome patients or in patients with classical Kaposi's sarcoma. The evidence suggests that interferon inactivators may play a role in the clinical manifestation of AIDS.
摘要
干扰素系统与获得性免疫缺陷综合征（艾滋病）的诊断及潜在治疗有关。在我们对艾滋病患者的研究中，我们发现了循环血清干扰素灭活剂的存在。在艾滋病前驱期患者或经典卡波西肉瘤患者中未检测到这些干扰素灭活剂。有证据表明，干扰素灭活剂可能在艾滋病的临床表现中起作用。
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