• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

脉络膜肿物作为小细胞肺癌的首发体征

Choroidal mass as the presenting sign of small cell lung carcinoma.

作者信息

Fernandes Bruno F, Fernandes Luiza Helena, Burnier Miguel N

机构信息

Department of Ophthalmology, Henry C. Witelson Ophthalmic Pathology Laboratory, McGill University Health Centre, Montreal, Quebec, Canada, and Department of Ophthalmology, Hospital dos Servidores do Estado, Rio de Janeiro, Brazil.

出版信息

Can J Ophthalmol. 2006 Oct;41(5):605-8. doi: 10.1016/S0008-4182(06)80032-3.

DOI:10.1016/S0008-4182(06)80032-3
PMID:17016534
Abstract

CASE REPORT

To report the case of a 58-year-old man with blurred vision and metamorphopsia who had an amelanotic choroidal mass in the right eye as the presenting sign of a small cell lung carcinoma. Systemic screening failed to reveal a tumor elsewhere, and the lesion was initially treated as a primary ocular tumor. Discovery of the primary site was made 10 months after the ocular diagnosis, and the patient was then treated with systemic chemotherapy and local radiation therapy.

COMMENTS

The ophthalmologist has a crucial role not only in the management of ocular metastases but also in the diagnosis of the primary nonocular malignancies that present as a choroidal mass. The possibility of ocular metastases in patients with choroidal masses should always be considered whether or not there is a diagnosis of cancer elsewhere.

摘要

病例报告

报告一名58岁男性病例,该患者因视力模糊和视物变形就诊,右眼有一无色素性脉络膜肿物,此为小细胞肺癌的首发体征。全身筛查未发现其他部位有肿瘤,该病变最初被当作原发性眼内肿瘤进行治疗。眼部诊断10个月后发现了原发部位,随后患者接受了全身化疗和局部放射治疗。

评论

眼科医生不仅在眼转移瘤的治疗中起着关键作用,而且在诊断表现为脉络膜肿物的原发性非眼恶性肿瘤方面也起着关键作用。无论其他部位是否已诊断出癌症,对于有脉络膜肿物的患者,都应始终考虑眼转移的可能性。

相似文献

1
Choroidal mass as the presenting sign of small cell lung carcinoma.脉络膜肿物作为小细胞肺癌的首发体征
Can J Ophthalmol. 2006 Oct;41(5):605-8. doi: 10.1016/S0008-4182(06)80032-3.
2
[Choroidal metastasis revealing pulmonary adenocarcinoma].
Rev Med Interne. 2006 Sep;27(9):699-701. doi: 10.1016/j.revmed.2006.06.003. Epub 2006 Jun 27.
3
Multiple bilateral choroidal metastatic tumors from a small-cell neuroendocrine carcinoma of unknown primary site.来自原发部位不明的小细胞神经内分泌癌的多发双侧脉络膜转移性肿瘤。
Eur J Ophthalmol. 2005 Jan-Feb;15(1):148-52. doi: 10.1177/112067210501500126.
4
Carcinoma lung presenting with choroidal metastasis as initial presentation: a rarity.以脉络膜转移为首发表现的肺癌:罕见病例。
J Cancer Res Ther. 2013 Jul-Sep;9(3):504-6. doi: 10.4103/0973-1482.119361.
5
Choroidal metastasis as a presenting manifestation of lung cancer: a report of 3 cases and systematic review of the literature.脉络膜转移作为肺癌的首发表现:3例报告及文献系统综述
Medicine (Baltimore). 2012 Jul;91(4):179-194. doi: 10.1097/MD.0b013e3182574a0b.
6
Simultaneous choroidal and brain metastasis as initial manifestations of lung cancer.同时发生脉络膜和脑转移作为肺癌的初始表现
Ophthalmic Surg Lasers. 2002 Jul-Aug;33(4):323-5.
7
[Choroidal metastases of lung neoplasm treated with external radiotherapy and polychemotherapy: a study of four clinical cases].[肺癌脉络膜转移瘤的外照射放疗及多药化疗治疗:4例临床病例研究]
J Fr Ophtalmol. 2012 Feb;35(2):122.e1-8. doi: 10.1016/j.jfo.2010.11.007. Epub 2011 Dec 20.
8
Choroidal metastases as the initial presentation of lung cancer: A rare scenario.脉络膜转移作为肺癌的首发表现:一种罕见情况。
Niger J Clin Pract. 2017 Jul;20(7):905-909. doi: 10.4103/1119-3077.212439.
9
Malignant bronchial Abrikossoff's tumor and small cell lung cancer: a case report and review.恶性支气管阿布里科索夫瘤与小细胞肺癌:一例报告及文献复习
Anticancer Res. 2001 Jan-Feb;21(1B):563-5.
10
[Secondary hypopituitarism due to hypothalamic metastasis from small cell lung cancer].[小细胞肺癌下丘脑转移所致继发性垂体功能减退]
Endocrinol Nutr. 2009 Apr;56(4):201-4. doi: 10.1016/S1575-0922(09)70985-4. Epub 2009 Jun 11.

引用本文的文献

1
Choroidal metastasis as the first sign of small cell lung cancer: A case report.脉络膜转移作为小细胞肺癌的首发症状:一例报告
Oncol Lett. 2025 Jul 18;30(4):451. doi: 10.3892/ol.2025.15197. eCollection 2025 Oct.
2
Regression of Bilateral Choroidal Metastases From Primary Lung Carcinoma in Response to Systemic Bevacizumab and Platinum Doublet.原发性肺癌双侧脉络膜转移灶对全身应用贝伐单抗和铂类双联化疗的反应性消退
Cureus. 2025 Jan 4;17(1):e76900. doi: 10.7759/cureus.76900. eCollection 2025 Jan.
3
A Case of Binocular Metastatic Choroidal Tumor Originating from Pulmonary Adenocarcinoma Successfully Treated with Molecular Target Therapy.
一例源自肺腺癌的双眼转移性脉络膜肿瘤经分子靶向治疗成功治愈的病例
Case Rep Ophthalmol. 2023 Sep 8;14(1):426-432. doi: 10.1159/000530130. eCollection 2023 Jan-Dec.
4
Choroidal metastasis as a presenting feature in a metastatic lung carcinoma.脉络膜转移作为转移性肺癌的首发特征。
GMS Ophthalmol Cases. 2022 May 20;12:Doc13. doi: 10.3205/oc000200. eCollection 2022.
5
Assessment of Serum Tumor Markers for Predicting Ocular Metastasis in Lung Adenocarcinoma: A Retrospective Study.血清肿瘤标志物评估对肺腺癌眼转移的预测价值:一项回顾性研究。
Dis Markers. 2020 Jun 25;2020:2102158. doi: 10.1155/2020/2102158. eCollection 2020.
6
Choroidal Metastasis as Initial Presentation in Adenocarcinoma of Lung: A Case Report.脉络膜转移作为肺癌腺癌的首发表现:一例报告
J Clin Diagn Res. 2017 Mar;11(3):XD04-XD06. doi: 10.7860/JCDR/2017/22533.9446. Epub 2017 Mar 1.
7
Complete Disappearance of Choroidal Metastasis from Lung Adenocarcinoma Treated with Bevacizumab and Chemotherapy.贝伐单抗联合化疗治疗肺腺癌脉络膜转移灶完全消失
Case Rep Ophthalmol Med. 2015;2015:142408. doi: 10.1155/2015/142408. Epub 2015 May 7.
8
Bilateral choroidal metastasis from non-small cell lung cancer.非小细胞肺癌双侧脉络膜转移
Case Rep Oncol Med. 2014;2014:858265. doi: 10.1155/2014/858265. Epub 2014 Sep 14.
9
Choroidal metastasis as the presenting feature of a non-small cell lung carcinoma with no apparent primary lesion identified by X-ray: A case report.以脉络膜转移为首发表现的非小细胞肺癌,X线未发现明显原发灶:一例报告
Oncol Lett. 2014 Oct;8(4):1886-1888. doi: 10.3892/ol.2014.2389. Epub 2014 Jul 28.
10
RPE Adenocarcinoma as the Presenting Sign of Bronchogenic Carcinoma: Diagnostic Dilemma in the Management of a Case.
Case Rep Ophthalmol Med. 2013;2013:786378. doi: 10.1155/2013/786378. Epub 2013 Mar 27.