Fernandes Bruno F, Fernandes Luiza Helena, Burnier Miguel N
Department of Ophthalmology, Henry C. Witelson Ophthalmic Pathology Laboratory, McGill University Health Centre, Montreal, Quebec, Canada, and Department of Ophthalmology, Hospital dos Servidores do Estado, Rio de Janeiro, Brazil.
Can J Ophthalmol. 2006 Oct;41(5):605-8. doi: 10.1016/S0008-4182(06)80032-3.
To report the case of a 58-year-old man with blurred vision and metamorphopsia who had an amelanotic choroidal mass in the right eye as the presenting sign of a small cell lung carcinoma. Systemic screening failed to reveal a tumor elsewhere, and the lesion was initially treated as a primary ocular tumor. Discovery of the primary site was made 10 months after the ocular diagnosis, and the patient was then treated with systemic chemotherapy and local radiation therapy.
The ophthalmologist has a crucial role not only in the management of ocular metastases but also in the diagnosis of the primary nonocular malignancies that present as a choroidal mass. The possibility of ocular metastases in patients with choroidal masses should always be considered whether or not there is a diagnosis of cancer elsewhere.
报告一名58岁男性病例,该患者因视力模糊和视物变形就诊,右眼有一无色素性脉络膜肿物,此为小细胞肺癌的首发体征。全身筛查未发现其他部位有肿瘤,该病变最初被当作原发性眼内肿瘤进行治疗。眼部诊断10个月后发现了原发部位,随后患者接受了全身化疗和局部放射治疗。
眼科医生不仅在眼转移瘤的治疗中起着关键作用,而且在诊断表现为脉络膜肿物的原发性非眼恶性肿瘤方面也起着关键作用。无论其他部位是否已诊断出癌症,对于有脉络膜肿物的患者,都应始终考虑眼转移的可能性。