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脉络膜转移作为转移性肺癌的首发特征。

Choroidal metastasis as a presenting feature in a metastatic lung carcinoma.

作者信息

Jain Mukesh, Parameswarappa Deepika C

机构信息

Anant Bajaj Retina Institute, MTC Campus, L V Prasad Eye Institute, Bhubaneswar, India.

Anant Bajaj Retina Institute, KAR Campus, L V Prasad Eye Institute, Hyderabad, India.

出版信息

GMS Ophthalmol Cases. 2022 May 20;12:Doc13. doi: 10.3205/oc000200. eCollection 2022.

DOI:10.3205/oc000200
PMID:35912129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9285108/
Abstract

We report a case of a 65-year-old female who presented to us with diminution of vision in the right eye. She was only able to perceive light in the right eye, and the left eye had a vision of 20/20, N6. Anterior segment examination in both eyes was unremarkable except for senile cataract in the left eye. Posterior segment examination revealed features of choroidal metastasis in both eyes and exudative retinal detachment in the right eye. Multimodal imaging helped in the further confirmation of metastatic lesions. Right-eye fundus autofluorescence showed hyperautofluorescent lesions, ultrasound B-scan showed an elevated mass lesion in the choroid with moderate to high internal echogenicity, and optical coherence tomography showed a lumpy-bumpy appearance of the retinal pigment epithelium as well as an elevated choroidal mass lesion beneath it. On detailed systemic evaluation, the primary site of cancer was found to be the lungs. The patient was referred to a pulmonologist and an oncologist for chemotherapy and further management.

摘要

我们报告一例65岁女性,因右眼视力下降前来就诊。她右眼仅能感知光线,左眼视力为20/20,N6。双眼前段检查未见明显异常,仅左眼有老年性白内障。后段检查发现双眼有脉络膜转移特征,右眼有渗出性视网膜脱离。多模态成像有助于进一步确诊转移性病变。右眼眼底自发荧光显示高自发荧光病变,超声B超显示脉络膜有一个隆起的肿块病变,内部回声中等至较高,光学相干断层扫描显示视网膜色素上皮呈凹凸不平外观,其下方有一个隆起的脉络膜肿块病变。经详细的全身评估,发现癌症的原发部位是肺部。该患者被转诊至肺科医生和肿瘤学家处进行化疗及进一步治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a00/9285108/12a6c443dbf1/OC-12-13-g-003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a00/9285108/623f1d5269c5/OC-12-13-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a00/9285108/7692d27755f8/OC-12-13-g-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a00/9285108/12a6c443dbf1/OC-12-13-g-003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a00/9285108/623f1d5269c5/OC-12-13-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a00/9285108/7692d27755f8/OC-12-13-g-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a00/9285108/12a6c443dbf1/OC-12-13-g-003.jpg

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引用本文的文献

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本文引用的文献

1
Bilateral Choroidal Metastases from Lung Adenocarcinoma: A Case Report.肺腺癌双侧脉络膜转移:一例报告
Case Rep Oncol. 2016 Sep 13;9(3):530-536. doi: 10.1159/000449154. eCollection 2016 Sep-Dec.
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Choroidal mass as the presenting sign of small cell lung carcinoma.脉络膜肿物作为小细胞肺癌的首发体征
Can J Ophthalmol. 2006 Oct;41(5):605-8. doi: 10.1016/S0008-4182(06)80032-3.
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Anti-angiogenic therapy: Prospects for treatment of ocular tumors.抗血管生成疗法:眼部肿瘤的治疗前景。
Semin Ophthalmol. 2006 Jul-Sep;21(3):151-60. doi: 10.1080/08820530500350787.
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Treatment of metastatic tumors of the choroid with proton beam irradiation.质子束照射治疗脉络膜转移性肿瘤。
Ophthalmology. 2005 Feb;112(2):337-43. doi: 10.1016/j.ophtha.2004.09.013.
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Choroidal metastasis in disseminated lung cancer: frequency and risk factors.播散性肺癌中的脉络膜转移:发生率及危险因素
Am J Ophthalmol. 2002 Sep;134(3):445-7. doi: 10.1016/s0002-9394(02)01580-5.
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Chemotherapy for treatment of choroidal metastases from breast carcinoma.乳腺癌脉络膜转移的化疗治疗
Am J Ophthalmol. 1982 Jan;93(1):102-6. doi: 10.1016/0002-9394(82)90707-3.
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Diagnosis and management of cancer metastatic to the uvea: a study of 70 cases.葡萄膜转移癌的诊断与治疗:70例病例研究
Ophthalmology. 1979 Jul;86(7):1336-49. doi: 10.1016/s0161-6420(79)35393-3.