Nyamathi Adeline M, Suhadev Mohanarani, Swaminathan Soumya, Fahey John L
School of Nursing, University of California, Los Angeles, Los Angeles, CA 90095-1702, USA.
AIDS Behav. 2007 Jul;11(4):619-27. doi: 10.1007/s10461-006-9173-8. Epub 2006 Oct 3.
Focus group discussions were conducted to assess factors that might impact participation of subgroups in Chennai for future HIV vaccine trials. The participants were 112 men and women representing the following: (1) transport workers; (2) clients who attended a sexually transmitted disease clinic; (3) injection drug users; (4) men having sex with men; (5) women in sex work; and (6) monogamous married women. Participants expressed an intense interest in future HIV vaccine trials. Willingness to participate in future trials included altruism and the desire to have a protective vaccine for the future. Assurances regarding stigma and confidentiality, and compensation for families in the event of a poor outcome with a future HIV vaccine trial were reported. Concerns also centered on the impact of seroconverting, and a possible increase in risk behaviors. The need for education and counseling about the dangers of engaging in risky behavior during and after participating in a future HIV vaccine trial is discussed.
开展了焦点小组讨论，以评估可能影响钦奈不同亚组参与未来艾滋病毒疫苗试验的因素。参与者为112名男性和女性，分别代表以下群体：（1）运输工人；（2）性病诊所的就诊者；（3）注射吸毒者；（4）男男性行为者；（5）性工作者；（6）一夫一妻制已婚妇女。参与者对未来的艾滋病毒疫苗试验表现出浓厚兴趣。参与未来试验的意愿包括利他主义以及希望未来能有预防性疫苗。报告了有关消除污名化和保密的保证，以及如果未来艾滋病毒疫苗试验结果不佳对家庭的补偿。担忧还集中在血清转化的影响以及危险行为可能增加的问题。讨论了在参与未来艾滋病毒疫苗试验期间及之后对从事危险行为的危害进行教育和咨询的必要性。
