Reiher J, Rivest J, Grand'Maison F, Leduc C P
Department of Neurology, University of Sherbrooke, School of Medicine, Que, Canada.
Electroencephalogr Clin Neurophysiol. 1991 Jan;78(1):12-7. doi: 10.1016/0013-4694(91)90013-t.
Low amplitude rhythmic discharges (RDs) closely associated in time and in spatial distribution to inter-ictal epileptiform discharges are not seen in scalp EEGs of patients with non-periodic focal epileptiform discharges (NPEDs) but they are unexpectedly common in patients with periodic lateralized epileptiform discharges (PLEDs). A classification of PLEDs into PLEDs Proper (PLEDs without RDs), and PLEDs Plus (PLEDs with RDs) is proposed. Such a classification is useful for an easier appreciation of PLEDs' pleomorphism. It underscores the changing periodicity of PLEDs and allows for a more inclusive definition of the phenomenon than the one reported by the literature. It also emphasizes the importance of recognizing RDs in scalp EEGs as transitional anomalies intercalated between inter-ictal PLEDs and ictal seizure discharges, analogous to those observed by Ralston in animal models. Indeed, the occurrence of recorded seizures is higher in patients with PLEDs Plus than in those with PLEDs Proper or NPEDs.
在非周期性局灶性癫痫样放电（NPEDs）患者的头皮脑电图中未观察到与发作间期癫痫样放电在时间和空间分布上密切相关的低振幅节律性放电（RDs），但在周期性一侧性癫痫样放电（PLEDs）患者中它们却意外地常见。本文提出将PLEDs分为真性PLEDs（无RDs的PLEDs）和附加性PLEDs（有RDs的PLEDs）。这样的分类有助于更轻松地认识PLEDs的多形性。它强调了PLEDs周期性的变化，并且与文献报道相比，能对该现象给出更具包容性的定义。它还强调了在头皮脑电图中识别RDs作为发作间期PLEDs和发作期癫痫放电之间插入的过渡性异常的重要性，这类似于Ralston在动物模型中观察到的情况。实际上，附加性PLEDs患者记录到癫痫发作的发生率高于真性PLEDs患者或NPEDs患者。
