Cirillo Teresa, Montuori Paolo, Mainardi Pierangela, Russo Imma, Triassi Maria, Amodio-Cocchieri Renata
Department of Food Science, University of Naples "Federico II", Portici, Naples, Italy.
J Environ Sci Health A Tox Hazard Subst Environ Eng. 2006;41(10):2089-107. doi: 10.1080/10934520600867854.
Multipathway exposure to polycyclic aromatic hydrocarbons (PAHs) and Pyrene (Py) was studied among children ages 7-9 living in two areas of the Campania Region (South-Italy) classified as urban and rural. During five consecutive days PAHs and Py were detected in air samples from outdoors, indoors (school and home), individuals at inhalatory levels, and in food and beverages (defined as food) consumed daily by each child. 1-hydroxypyrene (1-OHP) was detected in children's urine. Gender, weight and height of each subject were recorded, and the personal Body Mass Index (BMI) calculated. The type of home heating, the presence of smokers and the number of cigarettes smoked at home was determined. Total PAH and Py median concentrations in outdoor air from urban areas were 1.70 ng m(-3) and 0.19 ng m(-3), respectively while in rural areas they were 1.10 ng m(-3) and 0.14 ng m(-3). Indoor air total PAH and Py median concentrations were 2.50 ng m(-3) and 0.15 ng m(-3), respectively for urban areas, and 4.10 ng m(-3) and 0.15 ng m(-3) for rural areas. In food the total PAH and Py median levels were 10.44 and 0.81 microg kg(-1) in urban areas and 18.90 and 0.90 microg kg(-1) in rural areas. The median urinary levels of 1-OHP for urban and rural children were 0.07 and 0.06 micromol/mol creat., respectively. From these data, food appears to be the most relevant source of exposure to PAHs and Py. The Py intake from single (food or air) or total (food and air) pathways did not significantly correlate with the urinary 1-OHP excreted daily for each child during all 5 days of observation.
对居住在坎帕尼亚大区（意大利南部）两个分别划分为城市和农村地区的7至9岁儿童，研究了其多途径接触多环芳烃（PAHs）和芘（Py）的情况。在连续五天里，检测了户外、室内（学校和家庭）空气样本中的PAHs和Py、个体吸入水平以及每个儿童每日食用的食物和饮料（定义为食品）中的PAHs和Py。在儿童尿液中检测到了1-羟基芘（1-OHP）。记录了每个受试者的性别、体重和身高，并计算了个人体重指数（BMI）。确定了家庭供暖类型、是否有吸烟者以及家中吸烟数量。城市地区户外空气中PAH和Py的总中位浓度分别为1.70 ng m(-3)和0.19 ng m(-3)，而农村地区分别为1.10 ng m(-3)和0.14 ng m(-3)。城市地区室内空气中PAH和Py的总中位浓度分别为2.50 ng m(-3)和0.15 ng m(-3)，农村地区分别为4.10 ng m(-3)和0.15 ng m(-3)。食品中PAH和Py的总中位水平在城市地区为10.44和0.81 μg kg(-1)，在农村地区为18.90和0.90 μg kg(-1)。城市和农村儿童尿液中1-OHP的中位水平分别为0.07和0.06 μmol/mol肌酐。从这些数据来看，食品似乎是接触PAHs和Py的最主要来源。在观察的全部5天中，每个儿童通过单一（食品或空气）或总（食品和空气）途径摄入的Py与每日尿液中排出的1-OHP之间没有显著相关性。
