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猫的进行性骨化性纤维发育不良样病症

Fibrodysplasia ossificans progressiva-like condition in a cat.

作者信息

Asano Kazushi, Sakata Aki, Shibuya Hisashi, Kitagawa Masato, Teshima Kenji, Kato Yuka, Sasaki Yukie, Kutara Kenji, Seki Mamiko, Edamura Kazuya, Sato Tsuneo, Tanaka Shigeo

机构信息

Laboratory of Veterinary Surgery, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Kameino, Fujisawa, Japan.

出版信息

J Vet Med Sci. 2006 Sep;68(9):1003-6. doi: 10.1292/jvms.68.1003.

DOI:10.1292/jvms.68.1003
PMID:17019075
Abstract

Fibrodysplasia ossificans progressiva (FOP)-like condition was diagnosed in a Japanese domestic cat with stiffness, marked atrophy of the muscles, and limited mobility of all joints in both the pelvic limbs. Etretinate, a retinoid, was used for medical management; however, no improvement in the clinical signs was observed. Inheritance of the disorder has not yet been demonstrated. Furthermore, the clinical signs and histopathological findings of feline FOP-like condition in the present case differed from those of the previously reported cases.

摘要

一只日本家猫被诊断出患有进行性骨化性纤维发育不良(FOP)样病症,该猫出现僵硬、肌肉明显萎缩以及双侧后肢所有关节活动受限的症状。维甲酸类药物依曲替酯被用于药物治疗;然而,未观察到临床症状有改善。该病症的遗传情况尚未得到证实。此外,本病例中猫FOP样病症的临床症状和组织病理学发现与先前报道的病例不同。

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Bilateral fibrodysplasia ossificans affecting the masticatory muscles and causing irreversible trismus in a domestic shorthair cat.
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Animal models of fibrodysplasia ossificans progressiva.进行性骨化性纤维发育不良的动物模型。
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Animal models of typical heterotopic ossification.典型异位骨化的动物模型。
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