DNA肿瘤病毒转化细胞的特性。
Properties of cells transformed by DNA tumor viruses.
作者信息
Butel J S, Estes M K
出版信息
In Vitro. 1975 May-Jun;11(3):142-50. doi: 10.1007/BF02615422.
PMID:170196
Abstract
Transformation by the papovaviruses, SV40 and polyoma, is reviewed briefly, including factors that affect the frequency of transformation. Virus markers useful in the determination of the etiology of virus-free tumors are described, including viral DNA, viral mRNA, virus-induced antigens, and the rescue of infectious virus. Finally, the evidence that viral genes are involved in the maintenance of transformation is presented.
摘要
本文简要综述了乳头瘤病毒SV40和多瘤病毒的转化作用，包括影响转化频率的因素。描述了可用于确定无病毒肿瘤病因的病毒标志物，包括病毒DNA、病毒mRNA、病毒诱导抗原以及感染性病毒的拯救。最后，给出了病毒基因参与维持转化的证据。
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