Clarey J C, Irvine D R
Department of Psychology, Monash University, Clayton, Victoria, Australia.
J Comp Neurol. 1990 Nov 8;301(2):304-24. doi: 10.1002/cne.903010212.
The thalamic and cortical projections to acoustically responsive regions of the anterior ectosylvian sulcus were determined by identifying retrogradely labelled cells after physiologically guided iontophoretic injections of horseradish peroxidase. The medial division of the medial geniculate nucleus, the intermediate division of the posterior nuclear group, the principal division of the ventromedial nucleus, and the lateroposterior complex were consistently labelled after these injections, although each animal showed slightly different patterns of labelling. The suprageniculate nucleus and the lateral and medial divisions of the posterior nuclear group were also labelled in most experiments. The cortex of the suprasylvian sulcus was the most consistently and densely labelled cortical region; each experiment showed a slightly different pattern of labelling throughout the suprasylvian sulcus, with an overall tendency for greater labelling in the ventral (lateral) bank of the middle region of the sulcus. Other cortical regions labelled less consistently included the anterior ectosylvian sulcus itself, the insular cortex of the anterior sylvian gyrus, and the posterior rhinal sulcus. In three experiments the contralateral cortex was examined and a small number of labelled cells was located in the anterior ectosylvian and suprasylvian sulci. Input from extralemniscal auditory thalamus is compatible with previously described auditory response properties of anterior ectosylvian sulcus neurons. The results also confirm the presence of input from visual and multimodal regions of thalamus and cortex, and therefore support claims of overlap of modalities within the sulcus. This overlap, as well as input from motor regions, suggests that the anterior ectosylvian sulcal field serves a sensorimotor role.
通过在生理引导下向辣根过氧化物酶进行离子电渗注射后鉴定逆行标记的细胞，确定了丘脑和皮质向前外侧沟听觉反应区域的投射。内侧膝状核的内侧部、后核群的中间部、腹内侧核的主要部和后外侧复合体在这些注射后始终被标记，尽管每只动物的标记模式略有不同。在大多数实验中，上膝状核以及后核群的外侧和内侧部也被标记。上外侧沟皮质是标记最一致且最密集的皮质区域；每个实验在上外侧沟中显示出略有不同的标记模式，总体趋势是在沟中间区域的腹侧（外侧）壁标记更多。其他标记不太一致的皮质区域包括前外侧沟本身、前颞回的岛叶皮质和后鼻沟。在三个实验中检查了对侧皮质，在前外侧沟和上外侧沟中发现了少量标记细胞。来自丘脑外侧听区的输入与先前描述的前外侧沟神经元的听觉反应特性一致。结果还证实了来自丘脑和皮质视觉及多模态区域的输入的存在，因此支持了该沟内模态重叠的说法。这种重叠以及来自运动区域的输入表明，前外侧沟区域起着感觉运动的作用。
