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治疗引起的骨髓变化的磁共振成像

MR imaging of therapy-induced changes of bone marrow.

作者信息

Daldrup-Link Heike E, Henning Tobias, Link Thomas M

机构信息

Department of Radiology, University of California San Francisco, 505 Parnassus Ave., San Francisco, CA, 94143-0628, USA.

出版信息

Eur Radiol. 2007 Mar;17(3):743-61. doi: 10.1007/s00330-006-0404-1. Epub 2006 Sep 21.

DOI:10.1007/s00330-006-0404-1
PMID:17021706
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1797072/
Abstract

MR imaging of bone marrow infiltration by hematologic malignancies provides non-invasive assays of bone marrow cellularity and vascularity to supplement the information provided by bone marrow biopsies. This article will review the MR imaging findings of bone marrow infiltration by hematologic malignancies with special focus on treatment effects. MR imaging findings of the bone marrow after radiation therapy and chemotherapy will be described. In addition, changes in bone marrow microcirculation and metabolism after anti-angiogenesis treatment will be reviewed. Finally, new specific imaging techniques for the depiction of regulatory events that control blood vessel growth and cell proliferation will be discussed. Future developments are directed to yield comprehensive information about bone marrow structure, function and microenvironment.

摘要

血液系统恶性肿瘤骨髓浸润的磁共振成像（MR）可为骨髓细胞密度和血管分布提供非侵入性检测，以补充骨髓活检所提供的信息。本文将回顾血液系统恶性肿瘤骨髓浸润的MR成像表现，特别关注治疗效果。将描述放疗和化疗后骨髓的MR成像表现。此外，还将回顾抗血管生成治疗后骨髓微循环和代谢的变化。最后，将讨论用于描绘控制血管生长和细胞增殖的调节事件的新的特异性成像技术。未来的发展方向是获取有关骨髓结构、功能和微环境的全面信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/c11275c4f77b/330_2006_404_Fig12_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/5465351e5190/330_2006_404_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/05a6741daf62/330_2006_404_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/1c0dd2a124b6/330_2006_404_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/d7275151e84a/330_2006_404_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/e0b47e123405/330_2006_404_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/ad573cdbefcc/330_2006_404_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/46c4df6254d8/330_2006_404_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/fe6d552c1ce7/330_2006_404_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/40fb65e01ed1/330_2006_404_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/ccd0958cfbe1/330_2006_404_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/d68472878ee6/330_2006_404_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/c11275c4f77b/330_2006_404_Fig12_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/5465351e5190/330_2006_404_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/05a6741daf62/330_2006_404_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/1c0dd2a124b6/330_2006_404_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/d7275151e84a/330_2006_404_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/e0b47e123405/330_2006_404_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/ad573cdbefcc/330_2006_404_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/46c4df6254d8/330_2006_404_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/fe6d552c1ce7/330_2006_404_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/40fb65e01ed1/330_2006_404_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/ccd0958cfbe1/330_2006_404_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/d68472878ee6/330_2006_404_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e14/1797072/c11275c4f77b/330_2006_404_Fig12_HTML.jpg

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