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[小腿慢性严重缺血:治疗前影像学检查与血运重建方法]

[Chronic critical ischemia of the lower leg: pretherapeutic imaging and methods for revascularization].

作者信息

Treitl M, Ruppert V, Mayer A K, Degenhart C, Reiser M, Rieger J

机构信息

Institut für Klinische Radiologie, Innenstadt-Klinikum der Ludwig-Maximilians-Universität, Pettenkoferstrasse 8a, 80336 Munich, Germany.

出版信息

Radiologe. 2006 Nov;46(11):962-72. doi: 10.1007/s00117-006-1423-2.

DOI:10.1007/s00117-006-1423-2
PMID:17021909
Abstract

Each year 1-2% of patients with peripheral arterial occlusive disease (pAOD) develop critical limb ischemia (CLI), characterized by rest pain and peripheral ulcer or gangrene. This aggravation of the disease is accompanied by an increase of the 1-year mortality rate up to 25% and a similarly increased frequency of major amputation. We can choose between conservative, endovascular, and surgical procedures for an adequate therapy of the underlying vascular stenoses or occlusions. Yet, clear therapeutic recommendations only exist for suprapopliteal lesions. However, in a number of cases, especially in diabetics, target lesions have an infrapopliteal location. Since endovascular procedures have undergone significant improvement in the last few years, the following review discusses methods for infrapopliteal revascularization taking into consideration the newest publications on this topic.

摘要

每年,1%-2%的外周动脉闭塞性疾病(pAOD)患者会发展为严重肢体缺血(CLI),其特征为静息痛以及外周溃疡或坏疽。疾病的这种加重伴随着1年死亡率增至25%以及大截肢频率的类似增加。对于潜在的血管狭窄或闭塞的充分治疗,我们可以在保守治疗、血管内治疗和外科手术之间进行选择。然而,仅存在针对腘动脉上方病变的明确治疗建议。然而,在许多病例中,尤其是糖尿病患者,目标病变位于腘动脉下方。由于血管内治疗在过去几年中取得了显著进展,以下综述考虑到关于该主题的最新出版物,讨论了腘动脉下方血管重建的方法。

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本文引用的文献

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美国心脏病学会/美国心脏协会2005年外周动脉疾病(下肢、肾、肠系膜及腹主动脉)患者管理实践指南:血管外科学会/血管外科学会、心血管造影和介入学会、血管医学和生物学学会、介入放射学会及美国心脏病学会/美国心脏协会实践指南特别工作组(制定外周动脉疾病患者管理指南写作委员会)联合报告;得到美国心血管和肺康复协会、国家心肺血液研究所、血管护理学会、跨大西洋跨学会共识及血管疾病基金会认可。
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The prevalence of chronic critical lower limb ischaemia in a population of 20,000 subjects 40-69 years of age.在20000名年龄在40至69岁的受试者群体中慢性严重下肢缺血的患病率。
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Epidemiology and pathophysiology of lower extremity peripheral arterial disease.下肢外周动脉疾病的流行病学与病理生理学
J Endovasc Ther. 2006 Feb;13 Suppl 2:II3-9. doi: 10.1177/15266028060130S204.
7
Time-resolved contrast enhanced magnetic resonance angiography of the head and neck at 3.0 tesla: initial results.3.0特斯拉头部和颈部的时间分辨对比增强磁共振血管造影:初步结果
Invest Radiol. 2006 Feb;41(2):116-24. doi: 10.1097/01.rli.0000192416.19801.ca.
8
Sirolimus-eluting versus bare stents for bailout after suboptimal infrapopliteal angioplasty for critical limb ischemia: 6-month angiographic results from a nonrandomized prospective single-center study.西罗莫司洗脱支架与裸支架用于严重肢体缺血患者腘下血管成形术效果欠佳时的补救治疗:一项非随机前瞻性单中心研究的6个月血管造影结果
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9
Bypass versus angioplasty in severe ischaemia of the leg (BASIL): multicentre, randomised controlled trial.严重下肢缺血的搭桥术与血管成形术对比研究(BASIL):多中心随机对照试验
Lancet. 2005 Dec 3;366(9501):1925-34. doi: 10.1016/S0140-6736(05)67704-5.
10
Atherosclerotic disease: whole-body cardiovascular imaging with MR system with 32 receiver channels and total-body surface coil technology--initial clinical results.动脉粥样硬化疾病:采用具有32个接收通道的磁共振系统和全身表面线圈技术进行全身心血管成像——初步临床结果。
Radiology. 2006 Jan;238(1):280-91. doi: 10.1148/radiol.2381041532. Epub 2005 Nov 22.