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90Sr/90Y 间质内近距离治疗源径向剂量函数的实验测定

Experimental determination of the radial dose function of 90Sr/90Y IVBT sources.

作者信息

Holmes Shannon M, DeWerd Larry A, Micka John A

机构信息

University of Wisconsin-Madison, Department of Medical Physics, Madison, Wisconsin 53706, USA.

出版信息

Med Phys. 2006 Sep;33(9):3225-33. doi: 10.1118/1.2256068.

DOI:10.1118/1.2256068
PMID:17022216
Abstract

A series of measurements were undertaken using both high sensitivity radiochromic film and new lithium fluoride thermoluminescent dosimeters in a liquid water medium to define the radial dose function of 90Sr/90Y beta emitting intravascular brachytherapy sources more accurately. These measurements of a single 5 French source pellet served to verify current Monte Carlo transport models and extrapolation chamber measurements of the radial dose function, thus providing the recommended independent published measurements for g(r) of these sources. A slight deviation in the published radial dose function at depth leads the authors to recommend that treatment planning be performed using updated g(r) values from current Monte Carlo transport models verified by measurements such as those shown in this investigation.

摘要

在液态水介质中,使用高灵敏度放射变色薄膜和新型氟化锂热释光剂量计进行了一系列测量,以更准确地定义90Sr/90Yβ发射型血管内近距离治疗源的径向剂量函数。对单个5法国源丸粒的这些测量用于验证当前的蒙特卡罗传输模型和径向剂量函数的外推腔测量,从而为这些源的g(r)提供推荐的独立公开测量值。已发表的径向剂量函数在深度上存在轻微偏差,这使得作者建议使用当前蒙特卡罗传输模型中经本研究所示测量验证的更新g(r)值来进行治疗计划。

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