Dahan Valerie, Kimoff R John, Petrof Basil J, Benedetti Andrea, Diorio Diane, Trojan Daria A
Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, QC, Canada.
Arch Phys Med Rehabil. 2006 Oct;87(10):1352-6. doi: 10.1016/j.apmr.2006.07.256.
To determine the frequency, predictive factors, and symptoms predictive of sleep-disordered breathing (SDB) in fatigued postpoliomyelitis clinic patients.
Cross-sectional, retrospective chart review.
University-affiliated hospital postpolio clinic.
Postpolio clinic charts (N=590) were reviewed. Ninety-eight patients were included, and 492 patients were not included, primarily because of the lack of a polysomnogram.
Not applicable.
The Apnea-Hypopnea Index (AHI) calculated as the total number of sleep-related breathing events/total sleep time.
The frequency of SDB defined by an AHI score of 5 or more was 65% and by an AHI score of 10 or more was 50%. Obstructive hypopnea was the predominant form, occurring in 86%. Age, sex, age at acute polio, time since polio, weakness and respiratory difficulties at acute polio, bulbar involvement at acute polio and at evaluation, body mass index, pulmonary function measures, alcohol use, sedative drug use, smoking, fibromyalgia, kyphoscoliosis, and scoliosis and ear-nose-throat surgery were not predictive of SDB (AHI scores > or =5 and > or =10). Snoring was more common in subjects with SDB (AHI score > or =5 and > or =10). Some pulmonary function measures correlated with oxygen saturation during sleep in SDB (AHI scores > or =5).
SDB was very common in fatigued postpoliomyelitis clinic patients referred for sleep evaluation. Obstructive hypopnea was the most frequent type. In this preliminary study, snoring tended to predict SDB.
确定疲劳的脊髓灰质炎后门诊患者睡眠呼吸障碍（SDB）的发生率、预测因素及预测症状。
横断面回顾性病历审查。
大学附属医院脊髓灰质炎后门诊。
审查了脊髓灰质炎后门诊病历（N = 590）。纳入98例患者，未纳入492例患者，主要原因是缺乏多导睡眠图。
不适用。
呼吸暂停低通气指数（AHI），计算方法为与睡眠相关的呼吸事件总数/总睡眠时间。
AHI评分≥5定义的SDB发生率为65%，AHI评分≥10定义的SDB发生率为50%。阻塞性低通气是主要形式，发生率为86%。年龄、性别、急性脊髓灰质炎发病年龄、脊髓灰质炎后时间、急性脊髓灰质炎时的虚弱和呼吸困难、急性脊髓灰质炎时及评估时的延髓受累、体重指数、肺功能指标、饮酒、使用镇静药物、吸烟、纤维肌痛、脊柱后凸侧弯、脊柱侧弯及耳鼻喉手术均不能预测SDB（AHI评分≥5和≥10）。打鼾在SDB患者（AHI评分≥5和≥10）中更常见。一些肺功能指标与SDB患者（AHI评分≥5）睡眠期间的血氧饱和度相关。
在因睡眠评估而转诊的疲劳脊髓灰质炎后门诊患者中，SDB非常常见。阻塞性低通气是最常见的类型。在这项初步研究中，打鼾倾向于预测SDB。
