Hess B, Mikhailov A
Max-Planck-Institut für medizinische Forschung, Jahnstrasse 29, D-69120 Heidelberg, Germany.
Biophys Chem. 1996 Feb 8;58(3):365-8. doi: 10.1016/0301-4622(95)00109-3.
Theoretical study of an irreversible enzymic reaction with allosteric product activation reveals that, in small spatial volumes, it can undergo a transition to coherent spiking regime characterized by the presence of strong correlations between reaction events and the states of individual enzyme molecules.
对具有变构产物激活作用的不可逆酶促反应的理论研究表明,在小空间体积中,它可以转变为相干尖峰状态,其特征是反应事件与单个酶分子状态之间存在强相关性。