妇科恶性肿瘤中的染色体结构异常
Structural chromosomal abnormalities in gynecologic malignancies.
作者信息
Huber H, Knogler W, Karlic H, Akrad M, Söregi G, Schweizer D
机构信息
1st Dept. of Gynecology, University of Vienna, Austria.
出版信息
Cancer Genet Cytogenet. 1990 Dec;50(2):189-97. doi: 10.1016/0165-4608(90)90179-e.
PMID:1702358
Abstract
Surgical specimens taken from four patients with gynecologic malignancies were cultured, and metaphase chromosomes were prepared after staining with chromamycin-A, distamycin, and DAPI. Four specially selected karyotypes and their structural aberrations are discussed in this study and compared with those (also from carcinomas) previously described in the literature.
摘要
取自四名妇科恶性肿瘤患者的手术标本进行了培养，并用放线菌素A、偏端霉素和4',6-二脒基-2-苯基吲哚（DAPI）染色后制备中期染色体。本研究讨论了四个特别选定的核型及其结构畸变，并与文献中先前描述的那些核型（也来自癌）进行了比较。
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