Miori L, Vignini M, Rabbiosi G
Department of Human Pathology, Dermatology Section, University of Pavia, Italy.
Am J Dermatopathol. 1990 Dec;12(6):598-602. doi: 10.1097/00000372-199012000-00011.
A case of flagellate dermatitis after administration of bleomycin is reported in a patient with Hodgkin's disease. Histopathological and immunohistochemical analysis revealed a drug-induced skin toxic reaction rather than a lymphomatous infiltrate. Pigmentary changes observed after the early erythematous eruption were due to a postinflammatory effect.
报告了1例霍奇金病患者在使用博来霉素后发生的鞭毛虫皮炎。组织病理学和免疫组织化学分析显示这是一种药物性皮肤毒性反应,而非淋巴瘤浸润。早期红斑疹后观察到的色素沉着变化是由炎症后效应引起的。