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[侗族新生儿中Gγ和Aγ链的比例以及一例高Gγ值病例的基因定位]

[Rate of G gamma and A gamma chains in Dong ethnic newborns and gene mapping of a case with high G gamma value].

作者信息

Liu Y M, Nan G H, Chen S S, Liang Z Q, Yang S X, Wen M L

机构信息

Department of Biochemistry, Jiangxi Medical College, Nanchang.

出版信息

Yi Chuan Xue Bao. 1990;17(5):344-8.

PMID:1702653
Abstract

The G gamma to A gamma ratio of fetal hemoglobin in 120 cord blood samples of Dong ethnic newborns distributed over the Dong Autonomous Regions in Guangxi and Hunan provinces were determined with the method of polyacrylamide gel electrophoresis. The result showed that a case has the high G gamma value of 81.4% while 119 babies have the normal G gamma values of 56 to 76% (69.4 +/- 3.1%). The high G gamma case was identified as G gamma-AG gamma-A gamma/G gamma-A gamma genotype.

摘要

采用聚丙烯酰胺凝胶电泳法,对分布于广西和湖南侗族自治区的120例侗族新生儿脐血样本中的胎儿血红蛋白Gγ与Aγ比值进行了测定。结果显示,1例新生儿的Gγ值高达81.4%,而119例新生儿的Gγ值正常,为56%至76%(69.4±3.1%)。高Gγ值的这例新生儿被鉴定为Gγ-AGγ-Aγ/Gγ-Aγ基因型。

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