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工作场所被动吸烟与呼吸道症状之间的横断面关联和前瞻性关联。

Cross-sectional and prospective associations between passive smoking and respiratory symptoms at the workplace.

作者信息

Ho Sai Yin, Lam Tai Hing, Chung Siu Fung, Lam Ting Pui

机构信息

Department of Community Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong.

出版信息

Ann Epidemiol. 2007 Feb;17(2):126-31. doi: 10.1016/j.annepidem.2006.06.010. Epub 2006 Oct 5.

Abstract

PURPOSE

The purpose of the study is to investigate the cross-sectional and prospective relation between workplace secondhand smoke (SHS) exposure and respiratory symptoms.

METHODS

Cross-sectional data for workplace SHS exposure and respiratory symptoms were collected by using random digit dialing from 7336 never-smoking Hong Kong workers 15 years or older in 1997 to 1998. In the 2000 to 2001 follow-up, 2213 workers who remained never smoking, had the same SHS exposure status, worked at the same job for at least 2 years, and were not exposed to SHS at home at follow-up were included for prospective analysis.

RESULTS

Cross-sectionally, SHS was associated significantly with frequent colds, cough and phlegm, throat problems, and the presence of any respiratory symptoms with adjusted odds ratios of 1.89 (95% confidence interval [CI], 1.66-2.15), 1.65 (95% CI, 1.35-2.02), 1.88 (95% CI, 1.63-2.15), and 1.96 (95% CI, 1.75-2.20) at baseline, each having significant linear associations with duration of exposure. SHS was not associated with rhinitis. Prospectively, consistent SHS exposure increased the risk for cough and phlegm and any respiratory symptoms by 48% (12% to 97%) and 54% (13% to 109%), respectively.

CONCLUSIONS

This first non-Western population-based prospective study shows that workplace SHS exposure is associated significantly with frequent respiratory symptoms, both cross-sectionally and prospectively, thus providing strong evidence that the association is causal.

摘要

目的

本研究旨在调查工作场所二手烟暴露与呼吸道症状之间的横断面关系和前瞻性关系。

方法

1997年至1998年,通过随机数字拨号从7336名15岁及以上的非吸烟香港工人中收集了工作场所二手烟暴露和呼吸道症状的横断面数据。在2000年至2001年的随访中,纳入了2213名仍为非吸烟者、二手烟暴露状况相同、从事同一工作至少2年且在随访时家中未接触二手烟的工人进行前瞻性分析。

结果

横断面分析中,二手烟与频繁感冒、咳嗽和咳痰、咽喉问题以及任何呼吸道症状显著相关,基线时调整后的优势比分别为1.89(95%置信区间[CI],1.66 - 2.15)、1.65(95%CI,1.35 - 2.02)、1.88(95%CI,1.63 - 2.15)和1.96(95%CI,1.75 - 2.20),且各与暴露持续时间呈显著线性关系。二手烟与鼻炎无关。前瞻性分析中,持续的二手烟暴露使咳嗽和咳痰以及任何呼吸道症状的风险分别增加了48%(12%至97%)和54%(13%至109%)。

结论

这项首次基于非西方人群的前瞻性研究表明,工作场所二手烟暴露在横断面和前瞻性方面均与频繁的呼吸道症状显著相关,从而提供了有力证据证明这种关联是因果关系。

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