Mandler Raul N
MS Center, George Washington University, USA.
Autoimmun Rev. 2006 Oct;5(8):537-43. doi: 10.1016/j.autrev.2006.02.008. Epub 2006 Mar 21.
Neuromyelitis optica of Devic (NMO) is a syndrome which combines transverse myelitis and optic neuritis. For many years it was assumed that transverse myelitis and optic neuritis should be simultaneous, that optic neuritis should be bilateral, and that transverse myelitis must be complete. NMO was considered to be very rare. Through the 20th century there was a debate on whether NMO is a distinct nosologic entity or a form of MS. In 2005 it is now possible to distinguish NMO from MS on the basis of the clinical, imaging, serology and immunopathology profile. This distinction is necessary for the implementation of adequate treatments, as the relapsing form of the illness carries significant morbidity and mortality.
德维克视神经脊髓炎（NMO）是一种合并横贯性脊髓炎和视神经炎的综合征。多年来，人们一直认为横贯性脊髓炎和视神经炎应同时出现，视神经炎应为双侧性，且横贯性脊髓炎必须是完全性的。NMO曾被认为非常罕见。在20世纪，关于NMO是一种独特的疾病实体还是多发性硬化症的一种形式存在争议。2005年，现在可以根据临床、影像学、血清学和免疫病理学特征将NMO与MS区分开来。这种区分对于实施适当的治疗是必要的，因为该疾病的复发形式具有显著的发病率和死亡率。
