Fussnecker Brendon L, Smith Brian H, Mustard Julie A
Department of Entomology, Ohio State University, Columbus, OH, USA.
J Insect Physiol. 2006 Oct;52(10):1083-92. doi: 10.1016/j.jinsphys.2006.07.008. Epub 2006 Sep 5.
The biogenic amines octopamine and tyramine are believed to play a number of important roles in the behavior of invertebrates including the regulation of motor function. To investigate the role of octopamine and tyramine in locomotor behavior in honey bees, subjects were injected with a range of concentrations of octopamine, tyramine, mianserin or yohimbine. Continuous observation of freely moving worker bees was used to examine the effects of these treatments on the amount of time honey bees spent engaged in different locomotor behaviors such as walking, grooming, fanning and flying. All treatments produced significant shifts in behavior. Decreases in time spent walking and increases in grooming or stopped behavior were observed for every drug. However, the pattern of the shift depended on drug, time after injection and concentration. Flying behavior was differentially affected with increases in flying seen in octopamine treated bees, whereas those receiving tyramine showed a decrease in flying. Taken together, these data provide evidence that octopamine and tyramine modulate motor function in the honey bee perhaps via interaction with central pattern generators or through effects on sensory perception.
生物胺章鱼胺和酪胺被认为在无脊椎动物的行为中发挥着许多重要作用，包括运动功能的调节。为了研究章鱼胺和酪胺在蜜蜂运动行为中的作用，对实验对象注射了一系列浓度的章鱼胺、酪胺、米安色林或育亨宾。通过持续观察自由活动的工蜂，来检验这些处理对蜜蜂用于不同运动行为（如行走、梳理、扇风和飞行）的时间量的影响。所有处理都使行为产生了显著变化。每种药物都观察到行走时间减少，梳理或静止行为增加。然而，行为变化的模式取决于药物、注射后的时间和浓度。飞行行为受到不同影响，注射章鱼胺的蜜蜂飞行增加，而接受酪胺的蜜蜂飞行减少。综合来看，这些证据表明章鱼胺和酪胺可能通过与中枢模式发生器相互作用或通过对感觉感知的影响来调节蜜蜂的运动功能。
