Wernham B G J, Jerram R M
Veterinary Specialist Group, 97 Carrington Rd, UNITEC, Auckland, New Zealand.
N Z Vet J. 2006 Oct;54(5):248-52. doi: 10.1080/00480169.2006.36706.
An 8-month-old Labrador Retriever was referred with a history of ambiguous external genitalia.
Clitoromegaly within apparent vulval folds, and an adjacent subcutaneous mass were noticed on external examination. An intra-abdominal testicle, with epididymis and suspected vas deferens ducts, was found during exploratory celiotomy. Incision over the subcutaneous mass revealed the accompanying testicle. Clitoridectomy was performed and an os clitoris removed. Normal juvenile testes were diagnosed on histology of the gonads. Chromosomal studies revealed a normal 78, XY male chromosomal constitution. Due to the combination of a male karyotype (78, XY), the presence of testicular tissue in the gonads, and the appearance of the external genitalia, a diagnosis of male pseudohermaphroditism (MPH) was made.
This case presents the first report of MPH in a Labrador Retriever, and highlights the diagnostic steps recommended when confronted with a dog with ambiguous external genitalia.
一只8个月大的拉布拉多寻回犬因外生殖器不明确的病史前来就诊。
外部检查发现明显的阴唇皱襞内阴蒂增大，以及一个相邻的皮下肿块。在探索性剖腹术中发现一个位于腹腔内的睾丸，伴有附睾和疑似输精管。切开皮下肿块发现了与之相连的睾丸。进行了阴蒂切除术并切除了阴蒂骨。性腺组织学检查诊断为正常的幼年睾丸。染色体研究显示染色体组成为正常的78, XY男性。由于男性核型（78, XY）、性腺中存在睾丸组织以及外生殖器的外观，诊断为男性假两性畸形（MPH）。
本病例是拉布拉多寻回犬中MPH的首例报告，并强调了面对外生殖器不明确的犬只时推荐的诊断步骤。
